In this perspective article, we reflect on the recent debate about the existence of human
neurogenesis and discuss direct, and also indirect, support for the ongoing formation, and …

Alzheimer's disease (AD) is the most prevalent form of dementia. Cerebrovascular
dysfunction is one of the earliest events in the pathogenesis of AD, as well as in vascular …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is the most
common cause of dementia. Symptoms of AD include memory loss, disorientation, mood …

Transcription factors regulate multiple processes during brain development and in the adult
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …

Triazole scaffolds, a series of 5-membered heterocycles, are well known for their high
efficacy, low toxicity, and superior pharmacokinetics. Alzheimer's disease (AD) is the first …

In the adult hippocampus new neurons are generated in the dentate gyrus from neural
progenitor cells. Adult-born neurons integrate into the hippocampal circuitry and contribute …

In addition to increasing β-amyloid plaque deposition and tau tangle formation, inhibition of
neurogenesis has recently been observed in Alzheimer's disease (AD). This study …

Growing evidence suggests that drugs targeting neurogenesis and myelinization could be
novel therapeutic targets against Alzheimer's disease (AD). Intracerebroventricular (icv) …

Protein misfolding and aggregation result in induction of a number of neurodegenerative
diseases. In the present study, the anti-fibrillation activity of calycosin and its influence on the …

Neuropsychological studies reported that shift workers show reduced cognitive performance
and circadian dysfunctions which may impact structural and functional brain networks. Here …