FOXA1: a transcription factor with parallel functions in development and cancer
GM Bernardo, RA Keri - Bioscience reports, 2012 - portlandpress.com
When aberrant, factors critical for organ morphogenesis are also commonly involved in
disease progression. FOXA1 (forkhead box A1), also known as HNF3α (hepatocyte nuclear …
disease progression. FOXA1 (forkhead box A1), also known as HNF3α (hepatocyte nuclear …
GATA-3 and the regulation of the mammary luminal cell fate
The GATA family of transcription factors plays essential roles in the specification and
maintenance of differentiated cell types. GATA-3 was identified in a microarray screen of the …
maintenance of differentiated cell types. GATA-3 was identified in a microarray screen of the …
Positive cross-regulatory loop ties GATA-3 to estrogen receptor α expression in breast cancer
The transcription factor GATA-3 is required for normal mammary gland development, and its
expression is highly correlated with estrogen receptor α (ERα) in human breast tumors …
expression is highly correlated with estrogen receptor α (ERα) in human breast tumors …
LncRNA ZFPM2‐AS1 promotes lung adenocarcinoma progression by interacting with UPF1 to destabilize ZFPM2
S Han, D Cao, J Sha, X Zhu, D Chen - Molecular oncology, 2020 - Wiley Online Library
Lung adenocarcinoma (LUAD), a histological subclass of non‐small‐cell lung cancer, is
globally the leading cause of cancer‐related deaths. Long noncoding RNAs (lncRNAs) are …
globally the leading cause of cancer‐related deaths. Long noncoding RNAs (lncRNAs) are …
Multifaceted role of PRDM proteins in human cancer
The PR/SET domain family (PRDM) comprise a family of genes whose protein products
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
Oviductal secretion and gamete interaction
S Ghersevich, E Massa, C Zumoffen - Reproduction, 2015 - rep.bioscientifica.com
A reliable, easy to assess marker for fertility in agricultural species would be highly desirable
and Anti-Müllerian Hormone (AMH) is a promising candidate. This review summarizes …
and Anti-Müllerian Hormone (AMH) is a promising candidate. This review summarizes …
The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in …
Previously, we observed that wild yam (Dioscorea villosa) root extract (WYRE) was able to
activate GATA3 in human breast cancer cells targeting epigenome. This study aimed to find …
activate GATA3 in human breast cancer cells targeting epigenome. This study aimed to find …
Ovarian development in mice requires the GATA4-FOG2 transcription complex
NL Manuylov, FO Smagulova, L Leach, SG Tevosian - 2008 - journals.biologists.com
We have demonstrated previously that mammalian sexual differentiation requires both the
GATA4 and FOG2 transcriptional regulators to assemble the functioning testis. Here we …
GATA4 and FOG2 transcriptional regulators to assemble the functioning testis. Here we …
[HTML][HTML] Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation
Assembly of functioning testis and ovary requires a GATA4–FOG2 transcriptional complex.
To define the separate roles for GATA4 and FOG2 proteins in sexual development of the …
To define the separate roles for GATA4 and FOG2 proteins in sexual development of the …
Corticothalamic projection neuron development beyond subtype specification: Fog2 and intersectional controls regulate intraclass neuronal diversity
MJ Galazo, JG Emsley, JD Macklis - Neuron, 2016 - cell.com
Corticothalamic projection neurons (CThPN) are a diverse set of neurons, critical for function
of the neocortex. CThPN development and diversity need to be precisely regulated, but little …
of the neocortex. CThPN development and diversity need to be precisely regulated, but little …