Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Review of antimicrobial resistance in the environment and its relevance to environmental regulators

AC Singer, H Shaw, V Rhodes, A Hart - Frontiers in microbiology, 2016 - frontiersin.org
The environment is increasingly being recognized for the role it might play in the global
spread of clinically relevant antibiotic resistance. Environmental regulators monitor and …

[HTML][HTML] Development of botanicals to combat antibiotic resistance

PD Gupta, TJ Birdi - Journal of Ayurveda and integrative medicine, 2017 - Elsevier
The discovery of antibiotics in the previous century lead to reduction in mortality and
morbidity due to infectious diseases but their inappropriate and irrational use has resulted in …

The concept of an ideal antibiotic: implications for drug design

M Gajdács - Molecules, 2019 - mdpi.com
The emergence and spread of antibiotic-resistant pathogens is a major public health issue,
which requires global action of an intersectoral nature. Multidrug-resistant (MDR) pathogens …

A critical review on exploiting the pharmaceutical potential of plant endophytic fungi

S Gupta, P Chaturvedi, MG Kulkarni… - Biotechnology advances, 2020 - Elsevier
The escalating demand for secondary metabolites in international markets poses a severe
threat to many plant species. An unscrupulous collection is also the immediate challenge to …

Resistance genes and extracellular proteins relieve antibiotic stress on the anammox process

NS Fan, JJ Fu, DQ Huang, YL Ma, ZY Lu, RC Jin… - Water Research, 2021 - Elsevier
The anaerobic ammonium oxidation (anammox) process is regarded as a promising
approach to treat antibiotic-containing wastewater. Therefore, it is urgent to elucidate the …

Evolutionary mechanisms shaping the maintenance of antibiotic resistance

P Durão, R Balbontín, I Gordo - Trends in microbiology, 2018 - cell.com
Antibiotics target essential cellular functions but bacteria can become resistant by acquiring
either exogenous resistance genes or chromosomal mutations. Resistance mutations …

Macrolide and nonmacrolide resistance with mass azithromycin distribution

T Doan, L Worden, A Hinterwirth… - … England Journal of …, 2020 - Mass Medical Soc
Background Mass distribution of azithromycin to preschool children twice yearly for 2 years
has been shown to reduce childhood mortality in sub-Saharan Africa but at the cost of …

Photoexcited quantum dots for killing multidrug-resistant bacteria

CM Courtney, SM Goodman, JA McDaniel… - Nature materials, 2016 - nature.com
Multidrug-resistant bacterial infections are an ever-growing threat because of the shrinking
arsenal of efficacious antibiotics,,,. Metal nanoparticles can induce cell death, yet the toxicity …