Human placental oxygenation in late gestation: experimental and theoretical approaches

GA Nye, E Ingram, ED Johnstone… - The Journal of …, 2018 - Wiley Online Library
The placenta is crucial for life. It is an ephemeral but complex organ acting as the barrier
interface between maternal and fetal circulations, providing exchange of gases, nutrients …

Unveiling distribution of per-and polyfluoroalkyl substances in matched placenta-serum tetrads: novel implications for birth outcome mediated by placental vascular …

D Ji, Y Pan, X Qiu, J Gong, X Li, C Niu… - Environmental …, 2023 - ACS Publications
The placenta is pivotal for fetal development and maternal–fetal transfer of many
substances, including per-and polyfluoroalkyl substances (PFASs). However, the …

The role of morphology in mathematical models of placental gas exchange

AS Serov, C Salafia, DS Grebenkov… - Journal of Applied …, 2016 - journals.physiology.org
The performance of the placenta as a gas exchanger has a direct impact on the future health
of the newborn. To provide accurate estimates of respiratory gas exchange rates, placenta …

Understanding how porosity gradients can make a better filter using homogenization theory

MP Dalwadi, IM Griffiths… - Proceedings of the …, 2015 - royalsocietypublishing.org
Filters whose porosity decreases with depth are often more efficient at removing solute from
a fluid than filters with a uniform porosity. We investigate this phenomenon via an extension …

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta

WM Tun, G Poologasundarampillai… - Journal of The …, 2021 - royalsocietypublishing.org
Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …

Three-dimensional modeling of human placental terminal villi

RP Mayo, DS Charnock-Jones, GJ Burton, ML Oyen - Placenta, 2016 - Elsevier
Introduction Placental transport is the main factor affecting the health and development of
the fetus. Due to the placenta's geometrical and mathematical complexity, the structure …

A multiscale method to calculate filter blockage

MP Dalwadi, M Bruna, IM Griffiths - Journal of Fluid Mechanics, 2016 - cambridge.org
Filters that act by adsorbing contaminant onto their pore walls will experience a decrease in
porosity over time, and may eventually block. As adsorption will generally be greater …

A multiscale model of placental oxygen exchange: The effect of villous tree structure on exchange efficiency

M Lin, B Mauroy, JL James, MH Tawhai… - Journal of theoretical …, 2016 - Elsevier
The placenta is critical to fetal health during pregnancy as it supplies oxygen and nutrients to
maintain life. It has a complex structure, and alterations to this structure across spatial scales …

Transport across thin membranes: Effective solute flux jump

GA Zampogna, PG Ledda, F Gallaire - Physics of Fluids, 2022 - pubs.aip.org
A model to describe the transport across membranes of chemical species dissolved in an
incompressible flow is developed via homogenization. The asymptotic matching between …

Maternal high-fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity

JA Salati, VHJ Roberts, MC Schabel, JO Lo… - International Journal of …, 2019 - nature.com
Abstract Background In a Japanese macaque model of diet-induced obesity, we have
previously demonstrated that consumption of a high-fat,“Western-style” diet (WSD) is …