Objectives To systematically review the impact of antibiotic therapy in the neonatal period on
changes in the gut microbiota and/or antibiotic resistance development. Methods Data …

Neonatal sepsis can be classified into two subtypes depending upon whether the onset of
symptoms is before 72 hours of life (early‐onset neonatal sepsis—EONS) or later (late …

OBJECTIVES: To assess the risk factors antibiotic therapy and outcomes of multidrug-
resistant (MDR) Gram-negative bacilli (GNB) bacteremia in NICU patients. METHODS …

Antibiotic resistance is a public health crisis. The Institute of Medicine 1 has listed control
and reduction of infections caused by antibiotic-resistant pathogens in acute care settings as …

Objectives This study aimed to determine the prevalence of and risk factors for colonization
with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and …

Bloodstream infections (BSI) are a common cause of morbidity and mortality in neonatal
intensive care units (NICUs) worldwide. Table 1 highlights the adverse outcomes associated …

Fecal carriage of carbapenemase-producing Enterobacteriaceae (CPE) has not been
extensively investigated, except in the cases of selected patients at risk, mostly during …

The Increasing Challenge of Multidrug-Resistant Gram-Negativ... : Medicine The Increasing
Challenge of Multidrug-Resistant Gram-Negative Bacilli: Results of a 5-Year Active …

Sulbactam irreversibly inhibits the hydrolytic activity of β-lactamases. This compound is
commercially available in combination with either ampicillin or cefoperazone. In each …

Neonates hospitalized in NICU are at risk for healthcare associated infections because of
their poor immune defenses, related to gestational age, colonization of mucous membranes …