Immunosensor sensitivity, regenerability, and stability directly depend on the type of
antibodies used for the immunosensor design, quantity of immobilized molecules, remaining …

Industrial Purification of Pharmaceutical Antibodies: Development, Operation, and
Validation of Chromatography Processes Page 1 12 Industrial Purification of …

Outlining the fundamental principles by which all interactions occur, this reference focuses
on harnessing the biochemistry of bioorganic compounds in order to separate them …

Two components of human serum enhance human immunodeficiency virus type 1 (HIV-1)
infection and mask HIV-1 neutralising antibody activity. The first is heat-stable, unique to HIV …

Protein A affinity chromatography is often employed as a capture step to meet the purity,
yield, and throughput requirements for pharmaceutical antibody purification. However, a …

We describe a comprehensive evaluation of 12 Protein A stationary phases for capture of
biotherapeutics. We first examine the morphological properties of the stationary phases …

This paper describes three closely related experiments utilizing colloidal Au nanoparticles to
teach basic concepts in physical chemistry. This is done in the context of surface chemistry …

Monoclonal gammopathy is characterized by the presence of an M-protein in serum or urine
that has homogeneous structural and functional properties. It can occur in very high …

Sindbis virus can infect a broad range of insect and vertebrate cell types due to the
widespread distribution of the cellular receptor for the virus. The development of Sindbis …

We describe the performance characteristics of five Protein A affinity‐chromatography
sorbents (Sepharose Fast Flow, Poros 50, Poros LP, Prosep and Streamline) for purifying a …