Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

A fast impedance-based antimicrobial susceptibility test

DC Spencer, TF Paton, KT Mulroney, TJJ Inglis… - Nature …, 2020 - nature.com
There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

Nanotechnology approaches for rapid detection and theranostics of antimicrobial resistant bacterial infections

S Saxena, K Punjabi, N Ahamad, S Singh… - ACS biomaterials …, 2022 - ACS Publications
As declared by WHO, antimicrobial resistance (AMR) is a high priority issue with a pressing
need to develop impactful technologies to curb it. The rampant and inappropriate use of …

An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing

SJ Lin, PH Chao, HW Cheng, JK Wang, YL Wang… - Lab on a Chip, 2022 - pubs.rsc.org
Antimicrobial susceptibility testing (AST) is a key measure in clinical microbiology
laboratories to enable appropriate antimicrobial administration. During an AST, the …

Microfluidic devices for studying bacterial taxis, drug testing and biofilm formation

S Pérez‐Rodríguez, JM García‐Aznar… - Microbial …, 2022 - Wiley Online Library
Some bacteria have coevolved to establish symbiotic or pathogenic relationships with
plants, animals or humans. With human association, the bacteria can cause a variety of …

A 3D-printed microfluidic gradient concentration chip for rapid antibiotic-susceptibility testing

H Zhang, Y Yao, Y Hui, L Zhang, N Zhou… - Bio-Design and …, 2022 - Springer
The rise of antibiotic resistance as one of the most serious global public health threats has
necessitated the timely clinical diagnosis and precise treatment of deadly bacterial …

Antibiotic susceptibility test under a linear concentration gradient using travelling surface acoustic waves

Y Im, S Kim, J Park, HJ Sung, JS Jeon - Lab on a Chip, 2021 - pubs.rsc.org
An efficient and accurate antibiotic susceptibility test (AST) is indispensable for measuring
the antimicrobial resistance of pathogenic bacteria. A minimal inhibitory concentration (MIC) …

Isolation and quantification of extracellular vesicle-encapsulated microRNA on an integrated microfluidic platform

CY Sung, CC Huang, YS Chen, KF Hsu, GB Lee - Lab on a Chip, 2021 - pubs.rsc.org
Ovarian cancer (OvCa) is the most fatal among gynecological cancers and affects many
women worldwide. Since OvCa is prone to metastasis, which significantly increases …

YOLO algorithm for long-term tracking and detection of escherichia coli at different depths of microchannels based on microsphere positioning assistance

L Sun, Y Xu, Z Rao, J Chen, Z Liu, N Lu - Sensors, 2022 - mdpi.com
The effect evaluation of the antibiotic susceptibility test based on bacterial solution is of great
significance for clinical diagnosis and prevention of antibiotic abuse. Applying a microfluidic …

Recent developments of chip-based phenotypic antibiotic susceptibility testing

S Kim, F Masum, JS Jeon - BioChip Journal, 2019 - Springer
Antibiotic susceptibility testing (AST), the screening of effective types and dosages of
antibiotics, has become significantly important in the antimicrobial-resistance era over the …