Catalytic functionalization of indoles in a new dimension
M Bandini, A Eichholzer - Angewandte Chemie International …, 2009 - Wiley Online Library
Abstract 140 Years ago Adolf von Baeyer proposed the structure of a heteroaromatic
compound which revolutionized organic and medical chemistry: indole. After more than a …
compound which revolutionized organic and medical chemistry: indole. After more than a …
A decade update on solvent and catalyst-free neat organic reactions: a step forward towards sustainability
Particular success has been achieved in the synthesis of new products and in processes
since the twelve principles of “green chemistry” were formulated in the 1990s. These …
since the twelve principles of “green chemistry” were formulated in the 1990s. These …
Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update
K Laxmikeshav, P Kumari… - Medicinal Research …, 2022 - Wiley Online Library
This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
Synthesis and anticancer activity of 5-(3-indolyl)-1, 3, 4-thiadiazoles
A series of 5-(3-indolyl)-2-substituted-1, 3, 4-thiadiazoles 5a–m were synthesized and their
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …
Synthesis and biological evaluation of indolyl chalcones as antitumor agents
D Kumar, NM Kumar, K Akamatsu, E Kusaka… - Bioorganic & medicinal …, 2010 - Elsevier
A series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer
activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j …
activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j …
Katalytische Funktionalisierung von Indolen in einer neuen Dimension
M Bandini, A Eichholzer - Angewandte Chemie, 2009 - Wiley Online Library
Abstract Vor 140 Jahren schlug Adolf von Baeyer die Struktur für eine heteroaromatische
Verbindung vor, die die organische und medizinische Chemie nachhaltig veränderte: Indol …
Verbindung vor, die die organische und medizinische Chemie nachhaltig veränderte: Indol …
1, 2, 4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A
B Parrino, D Carbone, S Cascioferro… - European journal of …, 2021 - Elsevier
The inhibition or prevention of biofilm formation represents an emerging strategy in the war
against antibiotic resistance, interfering with key players in bacterial virulence. This …
against antibiotic resistance, interfering with key players in bacterial virulence. This …
Synthesis and antitumor activity of 2, 5-bis (3′-indolyl)-furans and 3, 5-bis (3′-indolyl)-isoxazoles, nortopsentin analogues
P Diana, A Carbone, P Barraja, G Kelter… - Bioorganic & medicinal …, 2010 - Elsevier
A series of novel 2, 5-bis (3′-indolyl) furans and 3, 5-bis (3′-indolyl) isoxazoles were
synthesized as antitumor agents. The antiproliferative activity was evaluated in vitro toward …
synthesized as antitumor agents. The antiproliferative activity was evaluated in vitro toward …
Catalytic application of room temperature ionic liquids:[bmim][MeSO 4] as a recyclable catalyst for synthesis of bis (indolyl) methanes. Ion-fishing by MALDI-TOF-TOF …
The catalytic application of room temperature ionic liquids (RTILs) has been explored to
catalyse the reaction of indole with aldehydes to afford bis (indolyl) methanes. The catalytic …
catalyse the reaction of indole with aldehydes to afford bis (indolyl) methanes. The catalytic …
Alkaloids and colon cancer: molecular mechanisms and therapeutic implications for cell cycle arrest
Cancer is the second most fatal disease worldwide, with colon cancer being the third most
prevalent and fatal form of cancer in several Western countries. The risk of acquisition of …
prevalent and fatal form of cancer in several Western countries. The risk of acquisition of …