Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
Role of reactive oxygen species in the progression of Alzheimer's disease
Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …
Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer's and Parkinson's disease therapeutics
Among the more promising treatments proposed for Alzheimer's disease (AD) and
Parkinson's disease (PD) are those reducing brain insulin resistance. The antidiabetics in …
Parkinson's disease (PD) are those reducing brain insulin resistance. The antidiabetics in …
Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews
R Majidazar, E Rezazadeh-Gavgani… - European journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease and the most
common cause of dementia. In this umbrella systematic review (SR), we summarized the …
common cause of dementia. In this umbrella systematic review (SR), we summarized the …
Mechanistic insights for drug repurposing and the design of hybrid drugs for Alzheimer's disease
D Padhi, T Govindaraju - Journal of Medicinal Chemistry, 2022 - ACS Publications
The heterogeneity and complex nature of Alzheimer's disease (AD) is attributed to several
genetic risk factors and molecular culprits. The slow pace and increasing failure rate of …
genetic risk factors and molecular culprits. The slow pace and increasing failure rate of …
[HTML][HTML] Memantine: updating a rare success story in pro-cognitive therapeutics
PK Tari, CG Parsons, GL Collingridge, G Rammes - Neuropharmacology, 2024 - Elsevier
The great potential for NMDA receptor modulators as druggable targets in
neurodegenerative disorders has been met with limited success. Considered one of the rare …
neurodegenerative disorders has been met with limited success. Considered one of the rare …
[HTML][HTML] Photobiomodulation in Alzheimer's disease—A complementary method to state-of-the-art pharmaceutical formulations and nanomedicine?
Alzheimer's disease (AD), as a neurodegenerative disorder, usually develops slowly but
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
Dance for people with Alzheimer's disease: a systematic review
A Ruiz-Muelle… - Current Alzheimer …, 2019 - ingentaconnect.com
Background: In recent years, several reviews have addressed the effectiveness of dance
therapy in dementia, healthy older adults, or the elderly in general. However, reviews …
therapy in dementia, healthy older adults, or the elderly in general. However, reviews …
Drug discovery and development targeting dementia
Dementia, most often associated with neurodegenerative diseases, affects millions of
people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …
people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …
[HTML][HTML] Memantine
B Kuns, A Rosani, P Patel, D Varghese - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Memantine - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …