The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or
contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting …

Toll-like receptors (TLRs) are a family of pattern recognition receptors that are best-known
for their role in host defence from infection. Emerging evidence also suggests that TLRs …

Background Porphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS) is one of the
major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation …

The article discusses the protective and destructive roles of cytokine responses against
periodontal infections. It stresses the activities and functions of the protein molecule …

The innate host response to lipopolysaccharide (LPS) obtained from Porphyromonas
gingivalis is unusual in that different studies have reported that it can be an agonist for Toll …

Background & Aims: Despite the ability to participate in immune responses and the
continuous presence of bacteria and bacterial products, functional responses of intestinal …

The interaction between bacteria and eukaryotic cells is complex; active processes must
exist that allow us to live harmoniously with the bacteria which normally live on and within …

The phenomenon of endotoxin tolerance has been widely investigated, but to date, the
molecular mechanisms of endotoxin tolerance remain to be resolved clearly. The discovery …

Members of the Toll-like receptor (TLR) family play key roles in both innate and adaptive
immune responses. TLR proteins enable host to recognize a large number of pathogen …

The ability of a host to sense invasion by pathogenic organisms and to respond
appropriately to control infection is paramount to survival. In the case of sepsis and septic …