Multiple pathways are involved in maintaining the genetic integrity of a cell after its exposure
to ionizing radiation. Although repair mechanisms such as homologous recombination and …

A widely held tenet of present day oncology is that tumor cells treated with anticancer agents
die from apoptosis, and that cells resistant to apoptosis are resistant to cancer treatment. We …

Toxicity of silver nanoparticles (AgNPs) is supported by many observations in literature, but
no mechanism details have been proved yet. Here we confirm and quantify the toxic …

Exposure of human tumor cell lines to different chemotherapeutic drugs, ionizing radiation,
and differentiating agents induced morphological, enzymatic, and ploidy changes …

Loss of control of genomic stability is central in the development of cancer, and p53, by
regulating normal responses to DNA damage and other forms of genotoxic stress, is a key …

Exposure of human tumor cell lines to moderate doses of anticancer agents induces
terminal proliferation arrest accompanied by morphologic and enzymatic changes that …

Incomplete combustion processes in diesel engines produce particulate matter (PM) that
significantly contributes to air pollution. Currently, there remains a knowledge gap in relation …

Flavonoids are polyphenolic compounds that occur ubiquitously in plants. They are
discussed to represent cancer preventive food components in a human diet that is rich in …

Thioredoxin reductase (TrxR) is overpressed in many human tumors and has a key role in
regulating intracellular redox balance. Recently, thioredoxin system has emerged as a …

Introduction 3. Interaction of UV radiation with the skin 3.1. The nature of the UV spectrum
3.2. UV radiation causes DNA damage and mutations 3.3. Mutations can lead to loss of cell …