Carbapenem-resistant Acinetobacter baumannii: A challenge in the intensive care unit

Y Jiang, Y Ding, Y Wei, C Jian, J Liu… - Frontiers in microbiology, 2022 - frontiersin.org
Carbapenem-resistant Acinetobacter baumannii (CRAB) has become one of the leading
causes of healthcare-associated infections globally, particularly in intensive care units …

Clinical and pathophysiological overview of Acinetobacter infections: a century of challenges

D Wong, TB Nielsen, RA Bonomo… - Clinical microbiology …, 2017 - Am Soc Microbiol
Acinetobacter is a complex genus, and historically, there has been confusion about the
existence of multiple species. The species commonly cause nosocomial infections …

Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study

J Quan, X Li, Y Chen, Y Jiang, Z Zhou… - The Lancet Infectious …, 2017 - thelancet.com
Background Polymyxin antibiotics are used as last-resort therapies to treat infections caused
by multidrug-resistant Gram-negative bacteria. The plasmid-mediated colistin resistance …

Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli

M Zeng, J Xia, Z Zong, Y Shi, Y Ni, F Hu, Y Chen… - Journal of Microbiology …, 2023 - Elsevier
The dissemination of carbapenem-resistant Gram-negative bacilli (CRGNB) is a global
public health issue. CRGNB isolates are usually extensively drug-resistant or pandrug …

Carbapenemases in Enterobacteriaceae: detection and antimicrobial therapy

X Cui, H Zhang, H Du - Frontiers in microbiology, 2019 - frontiersin.org
Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in
the past few years, posing great challenges to human health. The plasmid-mediated …

[HTML][HTML] Chinese guidelines for the diagnosis and treatment of hospital-acquired pneumonia and ventilator-associated pneumonia in adults (2018 Edition)

Y Shi, Y Huang, TT Zhang, B Cao, H Wang… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Pneumonia (draft)” was published in 1999 (1). Afterwards, a number of guidelines for
HAP/VAP have been published or updated at home and abroad (2-10). The definitions of …

[HTML][HTML] Metagenomic insights into the distribution of antibiotic resistome between the gut-associated environments and the pristine environments

J Zeng, Y Pan, J Yang, M Hou, Z Zeng… - Environment International, 2019 - Elsevier
Antibiotic resistance genes (ARGs) in the environment are promoted by anthropogenic
activities, which cause potential risks to human health. However, large-scale quantitative …

An area under the concentration–time curve threshold as a predictor of efficacy and nephrotoxicity for individualizing polymyxin B dosing in patients with carbapenem …

J Yang, S Liu, J Lu, T Sun, P Wang, X Zhang - Critical Care, 2022 - Springer
Background Evidence supports therapeutic drug monitoring of polymyxin B, but clinical data
for establishing an area under the concentration–time curve across 24 h at steady state …

Retrospective observational study from a Chinese network of the impact of combination therapy versus monotherapy on mortality from carbapenem-resistant …

X Wang, Q Wang, B Cao, S Sun, Y Zhang… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Data for a total of 164 bloodstream infection cases due to carbapenem-resistant
Enterobacteriaceae (CRE) from 2013 to 2017 were retrospectively collected from 36 tertiary …

Risk Factors for Acquired Stenotrophomonas maltophilia Pneumonia in Intensive Care Unit: A Systematic Review and Meta-Analysis

N Wang, C Tang, L Wang - Frontiers in Medicine, 2022 - frontiersin.org
Background and Aims: Stenotrophomonas maltophilia is increasingly found in critically ill
patients, but it is considered a pathogen of limited pathogenicity and therefore it is not often …