The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

The choroid plexus (ChP) is the principal source of cerebrospinal fluid (CSF), which has
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …

Accumulating evidence indicates that gut microbiota dysbiosis is associated with increased
blood–brain barrier (BBB) permeability and contributes to Alzheimer's disease (AD) …

In recent years there has been a resurgence of interest in brain barriers and various roles
their intrinsic mechanisms may play in neurological disorders. Such studies require suitable …

1. Per-and polyfluoroalkyl substances (PFAS) are a class of structurally diverse synthetic
organic chemicals that are chemically stable, resistant to degradation, and persistent in …

The adult brain functions within a well-controlled stable environment, the properties of which
are determined by cellular exchange mechanisms superimposed on the diffusion restraint …

Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …

Careful examination of relevant literature shows that many of the most cherished concepts of
the blood-brain barrier are incorrect. These include an almost mythological belief in its …

Well-known as one of the main sources of cerebrospinal fluid (CSF), the choroid plexuses
have been, and still remain, a relatively understudied tissue in neuroscience. The choroid …

Microglia are the immune cells of the central nervous system. They are suspected to play
important roles in adult synaptogenesis and in the development of the neuronal network …