In the natural environment, plants are exposed to a variety of biotic and abiotic stress
conditions that trigger rapid changes in the production and scavenging of reactive oxygen …

Reactive oxygen species (ROS), now appreciated for their cellular signaling capabilities,
have a dual role in cancer. On the one hand, ROS can promote protumorigenic signaling …

Mitochondria produce ATP via respiratory oxidation of organic acids and transfer of
electrons to O2 via the mitochondrial electron transport chain. This process produces …

Once thought of exclusively as damaging molecules, reactive oxygen species (ROS) are
becoming increasingly appreciated for the role they play in cellular signaling through redox …

Mitochondria serves a primary role in energy maintenance but also function to govern levels
of mitochondria-derived reactive oxygen species (mROS). ROS have long been established …

Excessive production of mitochondrial reactive oxygen species (mROS) is strongly
associated with mitochondrial and cellular oxidative damage, aging, and degenerative …

Insulin resistance is a major risk factor for numerous diseases, including type 2 diabetes and
cardiovascular disease. These disorders have dramatically increased in incidence with …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Mitochondrial oxidative stress, mitochondrial dysfunction, or both have been implicated in
insulin resistance. However, disentangling the individual roles of these processes in insulin …

Mitochondria possess a Ca 2+ transport system composed of separate Ca 2+ influx and
efflux pathways. Intramitochondrial Ca 2+ concentrations regulate oxidative …