The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Potential therapeutic applications of multifunctional host-defense peptides from frog skin as anti-cancer, anti-viral, immunomodulatory, and anti-diabetic agents

JM Conlon, M Mechkarska, ML Lukic, PR Flatt - Peptides, 2014 - Elsevier
Frog skin constitutes a rich source of peptides with a wide range of biological properties.
These include host-defense peptides with cytotoxic activities against bacteria, fungi …

Antimicrobial peptides from amphibian innate immune system as potent antidiabetic agents: a literature review and bioinformatics analysis

H Soltaninejad, H Zare-Zardini… - Journal of Diabetes …, 2021 - Wiley Online Library
Antimicrobial peptides, as an important member of the innate immune system, have various
biological activities in addition to antimicrobial activity. There are some AMPs with …

[HTML][HTML] Binding of amphipathic α-helical antimicrobial peptides to lipid membranes: Lessons from temporins B and L

AK Mahalka, PKJ Kinnunen - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
Temporins constitute a family of amphipathic α-helical antimicrobial peptides (AMP) and
contain some of the shortest cytotoxic peptides, comprised of only 10–14 residues. General …

DNA barcoding, phylogeny and systematics of Golden-backed frogs (Hylarana, Ranidae) of the Western Ghats-Sri Lanka biodiversity hotspot, with the description of …

SD Biju, S Garg, S Mahony, N Wijayathilaka… - Contributions to …, 2014 - brill.com
A systematic revision of the genus Hylarana in the Western Ghats-Sri Lanka biodiversity
hotspot is presented. Species delineation in Hylarana is complicated due to a lack of distinct …

Temporins: an approach of potential pharmaceutic candidates

SM Romero, AB Cardillo, MC Martínez Ceron… - Surgical …, 2020 - liebertpub.com
Antimicrobial peptides (AMPs), also known as host defense peptides, are small and mostly
polycationic molecules that form part of the innate immune response. There are currently …

Reflections on a systematic nomenclature for antimicrobial peptides from the skins of frogs of the family Ranidae

JM Conlon - Peptides, 2008 - Elsevier
Frogs belonging to the extensive family Ranidae represent a valuable source of
antimicrobial peptides with therapeutic potential but there is currently no consistent system …

From frog integument to human skin: dermatological perspectives from frog skin biology

IS Haslam, EW Roubos, ML Mangoni… - Biological …, 2014 - Wiley Online Library
For over a century, frogs have been studied across various scientific fields, including
physiology, embryology, neuroscience,(neuro) endocrinology, ecology, genetics …

Peptidomic analysis in the discovery of therapeutically valuable peptides in amphibian skin secretions

JM Conlon, M Mechkarska… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The emergence of multidrug-resistant microorganisms has necessitated a
search for new antimicrobial agents. Skin secretions of many frog species contain peptides …

Peptides with antimicrobial and anti-inflammatory activities that have therapeutic potential for treatment of acne vulgaris

S Popovic, E Urbán, M Lukic, JM Conlon - Peptides, 2012 - Elsevier
The pathogenesis of acne vulgaris is multifactorial involving infection of the pilosebaceous
unit with Propionibacterium acnes and a cytokine-mediated inflammatory response. Five …