Epigenetic control of pancreatic cancer metastasis

L Krauß, C Schneider, E Hessmann, D Saur… - Cancer and Metastasis …, 2023 - Springer
Surgical resection, when combined with chemotherapy, has been shown to significantly
improve the survival rate of patients with pancreatic ductal adenocarcinoma (PDAC) …

ALYREF-JunD-SLC7A5 axis promotes pancreatic ductal adenocarcinoma progression through epitranscriptome-metabolism reprogramming and immune evasion

Q Meng, Y Xie, K Sun, L He, H Wu, Q Zhang… - Cell Death …, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a kind of tumor lacking nutrients due to its
poor vascularity and desmoplasia. Recent studies have shown that cancer cells might …

Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma

X Wang, AP Kutschat, J Aggrey-Fynn… - Molecular Cancer …, 2023 - AACR
A major hurdle to the application of precision oncology in pancreatic cancer is the lack of
molecular stratification approaches and targeted therapy for defined molecular subtypes. In …

[HTML][HTML] Genomics-based tools for drug discovery and development: From network maps to efficacy prediction

J Fang, Q Chen, G Wu - Journal of Holistic Integrative Pharmacy, 2023 - Elsevier
Computing technology plays a crucial role in the field of drug discovery and development.
With the rapid development of genomics and the improvement of databases, the application …

Bauchspeicheldrüsen-krebs: Neuer Ansatz zur Überwindung von Therapieresistenzen

FH Hamdan - TumorDiagn u Ther, 2023 - thieme-connect.com
Bauchspeicheldrüsenkrebs gehört nach wie vor zu den tödlichsten Krebsarten überhaupt. In
Deutschland werden dieses Jahr voraussichtlich rund 21000 Menschen die Diagnose …