Chronic stress and depressive-like behaviors in basic neuroscience research have been
associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss …

Identifying brain alterations that contribute to suicidal thoughts and behaviors (STBs) are
important to develop more targeted and effective strategies to prevent suicide. In the last …

Importance Computational psychiatry studies have investigated how reinforcement learning
may be different in individuals with mood and anxiety disorders compared with control …

The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

The stress–diathesis model posits that suicide is the result of an interaction between state-
dependent (environmental) stressors and a trait-like diathesis or susceptibility to suicidal …

Experiences affect mood, which in turn affects subsequent experiences. Recent studies
suggest two specific principles. First, mood depends on how recent reward outcomes differ …

The cognitive model of depression has significantly influenced the understanding of
distorted cognitive processes in major depression; however, this model's conception of …

Abstract Purpose of Review The rising suicide rate in the USA will not be reversed without
improved risk assessment and prevention practices. To date, the best method for clinicians …

Anhedonia (hyposensitivity to rewards) and negative bias (hypersensitivity to punishments)
are core features of major depressive disorder (MDD), which could stem from abnormal …

Despite being considered primarily a mood disorder, major depressive disorder (MDD) is
characterized by cognitive and decision making deficits. Recent research has employed …