[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
Chaste: a test-driven approach to software development for biological modelling
Chaste ('Cancer, heart and soft-tissue environment') is a software library and a set of test
suites for computational simulations in the domain of biology. Current functionality has …
suites for computational simulations in the domain of biology. Current functionality has …
[HTML][HTML] Anatomically accurate high resolution modeling of human whole heart electromechanics: a strongly scalable algebraic multigrid solver method for nonlinear …
Electromechanical (EM) models of the heart have been used successfully to study
fundamental mechanisms underlying a heart beat in health and disease. However, in all …
fundamental mechanisms underlying a heart beat in health and disease. However, in all …
Cardiac arrhythmogenesis: roles of ion channels and their functional modification
M Lei, SC Salvage, AP Jackson, CLH Huang - Frontiers in Physiology, 2024 - frontiersin.org
Cardiac arrhythmias cause significant morbidity and mortality and pose a major public
health problem. They arise from disruptions in the normally orderly propagation of cardiac …
health problem. They arise from disruptions in the normally orderly propagation of cardiac …
An active strain electromechanical model for cardiac tissue
F Nobile, A Quarteroni… - International journal for …, 2012 - Wiley Online Library
We propose a finite element approximation of a system of partial differential equations
describing the coupling between the propagation of electrical potential and large …
describing the coupling between the propagation of electrical potential and large …
Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an …
Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure
cases. It has features of incomplete relaxation and increased stiffness of the left ventricle …
cases. It has features of incomplete relaxation and increased stiffness of the left ventricle …
Image-based personalization of cardiac anatomy for coupled electromechanical modeling
A Crozier, CM Augustin, A Neic, AJ Prassl… - Annals of biomedical …, 2016 - Springer
Computational models of cardiac electromechanics (EM) are increasingly being applied to
clinical problems, with patient-specific models being generated from high fidelity imaging …
clinical problems, with patient-specific models being generated from high fidelity imaging …
A numerical study of scalable cardiac electro-mechanical solvers on HPC architectures
We introduce and study some scalable domain decomposition preconditioners for cardiac
electro-mechanical 3D simulations on parallel HPC (High Performance Computing) …
electro-mechanical 3D simulations on parallel HPC (High Performance Computing) …
Reduced order modeling for cardiac electrophysiology and mechanics: New methodologies, challenges and perspectives
A Manzoni, D Bonomi, A Quarteroni - Mathematical and numerical …, 2018 - Springer
Reduced-order modeling techniques enable a remarkable speed up in the solution of the
parametrized electromechanical model for heart dynamics. Being able to rapidly …
parametrized electromechanical model for heart dynamics. Being able to rapidly …
Towards a computational framework for modeling the impact of aortic coarctations upon left ventricular load
Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta
are important tools for analyzing the mechanistic links between myocardial deformation and …
are important tools for analyzing the mechanistic links between myocardial deformation and …