HIV and aging: reconsidering the approach to management of comorbidities

KM Erlandson, MY Karris - Infectious Disease Clinics, 2019 - id.theclinics.com
Over the past 30 years, human immunodeficiency virus (HIV) has transformed from a near
uniformly fatal infection to a chronic condition, fueled in part by the tremendous efforts of …

HIV‐1, HAART and cancer: a complex relationship

A Shmakova, D Germini… - International journal of …, 2020 - Wiley Online Library
HIV infected people are at higher risk of developing cancer, although it is globally
diminished in the era of highly active antiretroviral treatment (HAART). Recently …

CD4/CD8 ratio and cancer risk among adults with HIV

JL Castilho, A Bian, CA Jenkins… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Independent of CD4 cell count, a low CD4/CD8 ratio in people with HIV (PWH)
is associated with deleterious immune senescence, activation, and inflammation, which may …

Deaths attributable to cancer in the US human immunodeficiency virus population during 2001–2015

MJ Horner, MS Shiels, RM Pfeiffer… - Clinical Infectious …, 2021 - academic.oup.com
Background Antiretroviral therapy (ART) has reduced mortality among people living with
human immunodeficiency virus (HIV), but cancer remains an important cause of death. We …

Measures of Longitudinal Immune Dysfunction and Risk of AIDS and Non-AIDS Defining Malignancies in Antiretroviral-Treated People With Human Immunodeficiency …

F Chammartin, A Mocroft, A Egle… - Clinical Infectious …, 2024 - academic.oup.com
Background Human immunodeficiency virus (HIV) infection leads to chronic immune
activation/inflammation that can persist in virally suppressed persons on fully active …

The pattern of non-AIDS-defining cancers in the HIV population: epidemiology, risk factors and prognosis. A review

M Franzetti, E Ricci, P Bonfanti - Current HIV research, 2019 - ingentaconnect.com
The advent of highly active antiretroviral therapy (HAART) has significantly reduced the
incidence of AIDS events, including AIDS-defining malignancies. Nevertheless, several …

[HTML][HTML] HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer

H Li, X Chi, R Li, J Ouyang, Y Chen - International journal of …, 2019 - ncbi.nlm.nih.gov
Background: Women infected with HIV are more likely to have aggressive cervical cancer,
and patients with HIV infection are often more severely ill than those without HIV infection …

[HTML][HTML] Immune reconstitution inflammatory syndrome associated Kaposi sarcoma

I Poizot-Martin, S Brégigeon, R Palich, AG Marcelin… - Cancers, 2022 - mdpi.com
Simple Summary Kaposi sarcoma (KS) incidence has declined substantially since the
advent of effective ART but it remains a frequent cancer among people living with HIV …

Excess cancer prevalence in men with HIV: a nationwide analysis of Medicaid data

SM Koroukian, G Zhou, SM Navale, NK Schiltz, U Kim… - Cancer, 2022 - Wiley Online Library
Background Cancer is one of the most common comorbidities in men living with HIV
(MLWH). However, little is known about the MLWH subgroups with the highest cancer …

[HTML][HTML] Patient and provider perceptions of a comprehensive care program for HIV-positive adults over 50 years of age: the formation of the Golden Compass HIV and …

ML Greene, JY Tan, SD Weiser, K Christopoulos… - PLoS …, 2018 - journals.plos.org
Objective People living with HIV (PLWH) are living longer and developing comorbidities and
aging-related syndromes. New care models are needed to address the combined burden …