Neutrophils are the first responders to infection and inflammation and are thus a critical
component of innate immune defense. Understanding the behavior of neutrophils as they …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Despite their cytotoxic capacity, neutrophils are often co-opted by cancers to promote
immunosuppression, tumor growth, and metastasis. Consequently, these cells have …

Research on tumor‐associated neutrophils (TAN) currently surges because of the well‐
documented strong clinical relevance of tumor‐infiltrating neutrophils. This relevance is …

Immunotherapies like the adoptive transfer of gene-engineered T cells and immune
checkpoint inhibitors are novel therapeutic modalities for advanced cancers. However, some …

The NLRP3 inflammasome is a cytosolic multimeric protein platform that leads to the
activation of the protease zymogen, caspase-1 (CASP1). Inflammasome activation mediates …

Simple Summary Tumor-associated neutrophils (TANs) may differentiate into different
patterns under the stimulation of different factors, and they play a dual role in the occurrence …

Background & Aims Chronic viral infections present serious public health challenges;
however, direct-acting antivirals (DAAs) are now able to cure nearly all patients infected with …

Neutrophils are immune cells with reported phenotypic and functional plasticity. Tumor-
associated neutrophils display many roles during cancer progression. Several tumor …

The tumor microenvironment (TME) is a significant contributor to cancer progression
containing complex connections between cellular and chemical components and provides a …