Adaptive strategies and ecological roles of phages in habitats under physicochemical stress

D Huang, R Xia, C Chen, J Liao, L Chen, D Wang… - Trends in …, 2024 - cell.com
Bacteriophages (phages) play a vital role in ecosystem functions by influencing the
composition, genetic exchange, metabolism, and environmental adaptation of microbial …

Unique relationships between phages and endospore-forming hosts

M Butala, A Dragoš - Trends in microbiology, 2023 - cell.com
As part of their survival strategy under harsh environmental conditions, endospore-forming
bacteria can trigger a sporulation developmental program. Although the regulatory cascades …

[HTML][HTML] Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY

A Prichard, J Lee, TG Laughlin, A Lee, KP Thomas… - Cell reports, 2023 - cell.com
We recently discovered that some bacteriophages establish a nucleus-like replication
compartment (phage nucleus), but the core genes that define nucleus-based phage …

Rapid assessment of changes in phage bioactivity using dynamic light scattering

T Dharmaraj, MJ Kratochvil, JD Pourtois, Q Chen… - PNAS …, 2023 - academic.oup.com
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-
resistant bacteria. However, these efforts are confounded by the instability of phage …

Bacteriophage Effectively Rescues Pneumonia Caused by Prevalent Multidrug-Resistant Klebsiella pneumoniae in the Early Stage

L Gan, H Fu, Z Tian, J Cui, C Yan, G Xue… - Microbiology …, 2022 - Am Soc Microbiol
Pneumonia caused by multidrug-resistant (MDR) Klebsiella pneumoniae of sequence types
ST11 and ST383 have highlighted the necessity for new therapies against these prevalent …

Investigating potential auxiliary anaerobic digestion activity of phage under polyvinyl chloride microplastic stress

B Zang, H Zhou, Y Zhao, D Sano, R Chen - Journal of Hazardous Materials, 2024 - Elsevier
Polyvinyl chloride (PVC) microplastics present in sewage were trapped in sludge, thereby
hindering anaerobic digestion performance of waste active sludge (WAS). Phages regulate …

How to tackle bacteriophages: The review of approaches with mechanistic insight

M Karczewska, P Strzelecki… - International Journal of …, 2023 - mdpi.com
Bacteriophage-based applications have a renaissance today, increasingly marking their use
in industry, medicine, food processing, biotechnology, and more. However, phages are …

Bacteriophage genome engineering for phage therapy to combat bacterial antimicrobial resistance as an alternative to antibiotics

SS Usman, AI Uba, E Christina - Molecular Biology Reports, 2023 - Springer
Bacteriophages (phages) are viruses that mainly infect bacteria and are ubiquitously
distributed in nature, especially to their host. Phage engineering involves nucleic acids …

Antimicrobial resistance expansion in pathogens: a review of current mitigation strategies and advances towards innovative therapy

MA Adefisoye, AO Olaniran - JAC-Antimicrobial Resistance, 2023 - academic.oup.com
The escalating problem of antimicrobial resistance (AMR) proliferation in clinically important
pathogens has become one of the biggest threats to human health and the global economy …

Stability study in selected conditions and biofilm-reducing activity of phages active against drug-resistant Acinetobacter baumannii

N Bagińska, I Grygiel, F Orwat, MA Harhala… - Scientific Reports, 2024 - nature.com
Acinetobacter baumannii is currently a serious threat to human health, especially to people
with immunodeficiency as well as patients with prolonged hospital stays and those …