Skin wound healing: normal macrophage function and macrophage dysfunction in diabetic wounds

SM Aitcheson, FD Frentiu, SE Hurn, K Edwards… - Molecules, 2021 - mdpi.com
Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

Selection of appropriate wound dressing for various wounds

C Shi, C Wang, H Liu, Q Li, R Li, Y Zhang… - … in bioengineering and …, 2020 - frontiersin.org
There are many factors involved in wound healing, and the healing process is not static. The
therapeutic effect of modern wound dressings in the clinical management of wounds is …

Guidelines on the diagnosis and treatment of foot infection in persons with diabetes (IWGDF 2019 update)

BA Lipsky, É Senneville, ZG Abbas… - Diabetes/metabolism …, 2020 - Wiley Online Library
Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

[PDF][PDF] IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

BA Lipsky, J Aragón-Sánchez, M Diggle… - Diabetes Metab Res …, 2016 - aogp.com.au
23. Do not select a specific type of dressing for a diabetic foot infection with the aim of
preventing an infection or improving its outcome (strong; high). 24. For diabetic foot …

Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review

LIF Moura, AMA Dias, E Carvalho, HC de Sousa - Acta biomaterialia, 2013 - Elsevier
Diabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to
high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral …

Inflammation and wound healing: the role of the macrophage

TJ Koh, LA DiPietro - Expert reviews in molecular medicine, 2011 - cambridge.org
The macrophage is a prominent inflammatory cell in wounds, but its role in healing remains
incompletely understood. Macrophages have many functions in wounds, including host …

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p …

R Shi, Y Jin, W Hu, W Lian, C Cao… - … of Physiology-Cell …, 2020 - journals.physiology.org
More and more evidence advises that circular RNAs (circRNAs) function critically in
regulating different disease microenvironments. Our previous study found that …

Exosomes derived from adipose mesenchymal stem cells promote diabetic chronic wound healing through SIRT3/SOD2

Y Zhang, X Bai, K Shen, L Luo, M Zhao, C Xu, Y Jia… - Cells, 2022 - mdpi.com
Chronic wounds resulting from diabetes are a major health concern in both industrialized
and developing countries, representing one of the leading causes of disability and death …

Bioactive injectable hydrogel dressings for bacteria-infected diabetic wound healing: a “pull–push” approach

K Zhang, C Yang, C Cheng, C Shi, M Sun… - … applied materials & …, 2022 - ACS Publications
Chronic diabetic wound healing remains a challenge due to the existence of excessive
danger molecules and bacteria in the inflammatory microenvironment. There is an urgent …

From inflammation to current and alternative therapies involved in wound healing

MB Serra, WA Barroso, NN Silva… - International journal …, 2017 - Wiley Online Library
Wound healing is a complex event that develops in three overlapping phases: inflammatory,
proliferative, and remodeling. These phases are distinct in function and histological …