[HTML][HTML] Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …
of worldwide age-related cognitive decline and dementia. In the absence of effective …
[HTML][HTML] Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
[HTML][HTML] Deep learning encodes robust discriminative neuroimaging representations to outperform standard machine learning
Recent critical commentaries unfavorably compare deep learning (DL) with standard
machine learning (SML) approaches for brain imaging data analysis. However, their …
machine learning (SML) approaches for brain imaging data analysis. However, their …
Machine learning framework for early MRI-based Alzheimer's conversion prediction in MCI subjects
Mild cognitive impairment (MCI) is a transitional stage between age-related cognitive
decline and Alzheimer's disease (AD). For the effective treatment of AD, it would be …
decline and Alzheimer's disease (AD). For the effective treatment of AD, it would be …
What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus
What can be expected in normal aging, and where does normal aging stop and pathological
neurodegeneration begin? With the slow progression of age-related dementias such as …
neurodegeneration begin? With the slow progression of age-related dementias such as …
Beneficial effects of physical exercise on neuroplasticity and cognition
K Hötting, B Röder - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The human brain adapts to changing demands by altering its functional and structural
properties (“neuroplasticity”) which results in learning and acquiring skills. Convergent …
properties (“neuroplasticity”) which results in learning and acquiring skills. Convergent …
[HTML][HTML] Docosahexaenoic acid and cognition throughout the lifespan
MJ Weiser, CM Butt, MH Mohajeri - Nutrients, 2016 - mdpi.com
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid
(PUFA) found in the brain and can affect neurological function by modulating signal …
(PUFA) found in the brain and can affect neurological function by modulating signal …
White matter hyperintensities and imaging patterns of brain ageing in the general population
White matter hyperintensities are associated with increased risk of dementia and cognitive
decline. The current study investigates the relationship between white matter …
decline. The current study investigates the relationship between white matter …
[HTML][HTML] Loss of brain aerobic glycolysis in normal human aging
The normal aging human brain experiences global decreases in metabolism, but whether
this affects the topography of brain metabolism is unknown. Here we describe PET-based …
this affects the topography of brain metabolism is unknown. Here we describe PET-based …
Playing Super Mario induces structural brain plasticity: gray matter changes resulting from training with a commercial video game
Video gaming is a highly pervasive activity, providing a multitude of complex cognitive and
motor demands. Gaming can be seen as an intense training of several skills. Associated …
motor demands. Gaming can be seen as an intense training of several skills. Associated …