Pharmacotherapies and personalized medicine for alcohol use disorder: a review

FW Lohoff - Pharmacogenomics, 2020 - Taylor & Francis
Alcohol use disorder (AUD) is highly prevalent and among the leading causes of morbidity
and mortality in the United States. Pharmacotherapies for AUD are limited, thus making …

Platelet SERT as a peripheral biomarker of serotonergic neurotransmission in the central nervous system

S Yubero-Lahoz, P Robledo, M Farré… - Current medicinal …, 2013 - ingentaconnect.com
Alterations in serotonergic activity have been observed in many pathological conditions,
including neuropsychiatric diseases, irritable bowel syndrome, and hypertension. The …

The case for borderline personality disorder as an emotional disorder: Implications for treatment.

S Sauer-Zavala, DH Barlow - Clinical Psychology: Science and …, 2014 - psycnet.apa.org
The goal of this article is to advance understanding of borderline personality disorder (BPD)
as an emotional disorder and to use this information as a heuristic for reconceptualizing …

BDNF Val66Met polymorphism and plasma levels in Chinese Han population with obsessive-compulsive disorder and generalized anxiety disorder

Y Wang, H Zhang, Y Li, Z Wang, Q Fan, S Yu… - Journal of affective …, 2015 - Elsevier
Background Anxiety disorders are a category of mental disorders characterized by feelings
of anxiety and fear, which include generalized anxiety disorder (GAD). Obsessive …

Serotonin transporter gene polymorphism (5-HTTLPR) L allele interacts with stress to increase anxiety symptoms in Chinese adolescents: a multiwave longitudinal …

Q Ming, Y Zhang, J Yi, X Wang, X Zhu, S Yao - BMC psychiatry, 2015 - Springer
Background Previous studies of the interaction between a functional polymorphism in the
serotonin transporter gene-linked promoter region (5-HTTLPR) and stress in anxiety-related …

The role of pharmacogenetics in the treatment of anxiety disorders and the future potential for targeted therapeutics

M Scherf-Clavel, H Weber, J Deckert… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Anxiety disorders (AD) are among the most common mental disorders
worldwide. Pharmacotherapy, including benzodiazepines, selective serotonin reuptake …

[HTML][HTML] 5HTTLPR polymorphism and postpartum depression risk: A meta-analysis

J Li, Y Chen, Q Xiang, J Xiang, Y Tang, L Tang - Medicine, 2020 - journals.lww.com
Objective: Postpartum depression (PPD) is an episode of major depressive disorder that
affecting women of childbearing age. 5-HTTLPR is 1 of the most extensively investigated …

Association of 5-HTTLPR With Post-Traumatic Stress Disorder in US Service Members

XZ Hu, RJ Ursano, D Benedek, X Li… - Chronic …, 2024 - journals.sagepub.com
Objective Post-traumatic stress disorder (PTSD) is a mental disorder that manifests after
exposure to a stressful traumatic event, such as combat experience. Accumulated evidence …

Response to citalopram is not associated with SLC6A4 genotype in African-Americans and Caucasians with major depression

RE Poland, IM Lesser, YJY Wan, L Gertsik, J Yao… - Life sciences, 2013 - Elsevier
AIMS: Ethnic differences in genotype frequency provide a natural condition for assessing the
contribution of gene variations to the causes and treatments of disease. Accordingly, the …

Pharmacogenetics of anxiety disorders

OO McGowan - Neuroscience letters, 2020 - Elsevier
Anxiety disorders are common and disabling conditions the treatment of which remains a
challenge. While different groups of medication are available for their treatment, a …