Post-transcriptional gene regulation by mRNA modifications
The recent discovery of reversible mRNA methylation has opened a new realm of post-
transcriptional gene regulation in eukaryotes. The identification and functional …
transcriptional gene regulation in eukaryotes. The identification and functional …
The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies
AT Amare, KO Schubert, M Klingler-Hoffmann… - Translational …, 2017 - nature.com
Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …
studies have identified genetic variants associated with cardiovascular diseases, metabolic …
Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders
RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …
have highlighted the public health relevance of this association, insofar as both conditions …
Reversible RNA adenosine methylation in biological regulation
N 6-methyladenosine (m 6 A) is a ubiquitous modification in mRNA and other RNAs across
most eukaryotes. For many years, however, the exact functions of m 6 A were not clearly …
most eukaryotes. For many years, however, the exact functions of m 6 A were not clearly …
N6-methyladenosine and neurological diseases
N Zhang, C Ding, Y Zuo, Y Peng, L Zuo - Molecular neurobiology, 2022 - Springer
Abstract N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the
adenosine N6 position and is the most common chemical epigenetic modification among …
adenosine N6 position and is the most common chemical epigenetic modification among …
Depression with atypical features and increase in obesity, body mass index, waist circumference, and fat mass: a prospective, population-based study
AM Lasserre, J Glaus, CL Vandeleur… - JAMA …, 2014 - jamanetwork.com
Importance Depression and obesity are 2 prevalent disorders that have been repeatedly
shown to be associated. However, the mechanisms and temporal sequence underlying this …
shown to be associated. However, the mechanisms and temporal sequence underlying this …
Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations
Y Milaneschi, F Lamers, WJ Peyrot, BT Baune… - JAMA …, 2017 - jamanetwork.com
Importance The association between major depressive disorder (MDD) and obesity may
stem from shared immunometabolic mechanisms particularly evident in MDD with atypical …
stem from shared immunometabolic mechanisms particularly evident in MDD with atypical …
miR-149-3p regulates the switch between adipogenic and osteogenic differentiation of BMSCs by targeting FTO
Bone marrow-derived mesenchymal stem cells (BMSCs) have been suggested to possess
the capacity to differentiate into different cell lineages. Maintaining a balanced stem cell …
the capacity to differentiate into different cell lineages. Maintaining a balanced stem cell …
The importance of gene–environment interactions in human obesity
The worldwide obesity epidemic has been mainly attributed to lifestyle changes. However,
who becomes obese in an obesity-prone environment is largely determined by genetic …
who becomes obese in an obesity-prone environment is largely determined by genetic …
Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice
S Liu, J Xiu, C Zhu, K Meng, C Li, R Han, T Du… - Nature …, 2021 - nature.com
Post-transcriptional modifications of RNA, such as RNA methylation, can epigenetically
regulate behavior, for instance learning and memory. However, it is unclear whether RNA …
regulate behavior, for instance learning and memory. However, it is unclear whether RNA …