1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

To evaluate the effect of vitamin D 3 supplementation on cancer mortality in the general
population and on prognosis in cancer patients, a systematic review and meta-analysis of …

Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …

Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

Background Efficacy of vitamin D supplementation may vary by dosing strategies and
adiposity. To address such heterogeneity, we performed a meta-analysis of randomised …

Whether supplemental vitamin D reduces risk of cancer or cardiovascular disease (CVD) is
relatively unexplored in randomized trial settings. The VITamin D and OmegA-3 TriaL …

Background: Vitamin D has been linked with improved cancer outcome. This systematic
review and meta-analysis investigates the relationship between cancer outcomes and both …