Endolysin, a promising solution against antimicrobial resistance

M Rahman, W Wang, Q Sun, JA Shah, C Li, Y Sun, Y Li… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) is a global crisis for human public health which threatens the
effective prevention and control of ever-increasing infectious diseases. The advent of …

Bacteriophage endolysins as novel antimicrobials

M Schmelcher, DM Donovan, MJ Loessner - Future microbiology, 2012 - Taylor & Francis
Endolysins are enzymes used by bacteriophages at the end of their replication cycle to
degrade the peptidoglycan of the bacterial host from within, resulting in cell lysis and release …

Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application

KM Danis-Wlodarczyk, DJ Wozniak, ST Abedon - Antibiotics, 2021 - mdpi.com
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …

Bacteriophage endolysins—current state of research and applications

MJ Loessner - Current opinion in microbiology, 2005 - Elsevier
Endolysins are phage-encoded enzymes that break down bacterial peptidoglycan at the
terminal stage of the phage reproduction cycle. Their action is tightly regulated by holins, by …

Potential for bacteriophage endolysins to supplement or replace antibiotics in food production and clinical care

MJ Love, D Bhandari, RCJ Dobson, C Billington - Antibiotics, 2018 - mdpi.com
There is growing concern about the emergence of bacterial strains showing resistance to all
classes of antibiotics commonly used in human medicine. Despite the broad range of …

Exogenous glucosinolate produced by Arabidopsis thaliana has an impact on microbes in the rhizosphere and plant roots

M Bressan, MA Roncato, F Bellvert, G Comte… - The ISME …, 2009 - academic.oup.com
A specificity of Brassicaceous plants is the production of sulphur secondary metabolites
called glucosinolates that can be hydrolysed into glucose and biocidal products. Among …

[图书][B] Genetic Resources, Chromosome Engineering, and Crop Improvement: Cereals, Volume 2

RJ Singh, PP Jauhar - 2006 - taylorfrancis.com
Summarizing landmark research, Volume 2 of this essential series furnishes information on
the availability of germplasm resources that breeders can exploit for producing high-yielding …

Impact of genetically modified crops on soil‐and plant‐associated microbial communities

KE Dunfield, JJ Germida - Journal of environmental quality, 2004 - Wiley Online Library
Transgenic or genetically modified plants possess novel genes that impart beneficial
characteristics such as herbicide resistance. One of the least understood areas in the …

Microbial diversity in soil: ecological theories, the contribution of molecular techniques and the impact of transgenic plants and transgenic microorganisms

JM Lynch, A Benedetti, H Insam, MP Nuti… - Biology and fertility of …, 2004 - Springer
This review mainly discusses three related topics: the application of ecological theories to
soil, the measurement of microbial diversity by molecular techniques and the impact of …

Lytic activity of the recombinant staphylococcal bacteriophage ΦH5 endolysin active against Staphylococcus aureus in milk

JM Obeso, B Martínez, A Rodríguez, P García - International journal of food …, 2008 - Elsevier
The endolysin gene (lysH5) from the genome of the Staphylococcus aureus bacteriophage
ΦH5 was cloned in Escherichia coli and characterized. The lysH5 gene encoded a protein …