Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Melatonin and health: insights of melatonin action, biological functions, and associated disorders

SB Ahmad, A Ali, M Bilal, SM Rashid, AB Wani… - Cellular and Molecular …, 2023 - Springer
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

The critical role of zinc in plants facing the drought stress

M Umair Hassan, M Aamer, M Umer Chattha, T Haiying… - Agriculture, 2020 - mdpi.com
Drought stress affects plant growth and development by altering physiological and
biochemical processes resulting in reduced crop productivity. Zinc (Zn) is an essential …

[HTML][HTML] Melatonin synthesis and function: evolutionary history in animals and plants

D Zhao, Y Yu, Z Zhao, R Sharma… - Frontiers in …, 2019 - frontiersin.org
Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

Melatonin: A master regulator of plant development and stress responses

C Sun, L Liu, L Wang, B Li, C Jin… - Journal of Integrative …, 2021 - Wiley Online Library
Melatonin is a pleiotropic molecule with multiple functions in plants. Since the discovery of
melatonin in plants, numerous studies have provided insight into the biosynthesis …

[HTML][HTML] Sleep loss can cause death through accumulation of reactive oxygen species in the gut

A Vaccaro, YK Dor, K Nambara, EA Pollina, C Lin… - Cell, 2020 - cell.com
The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

Functions and prospects of melatonin in plant growth, yield, and quality

K Wang, Q Xing, GJ Ahammed… - Journal of Experimental …, 2022 - academic.oup.com
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is an indole molecule widely found in
animals and plants. It is well known that melatonin improves plant resistance to various …

Melatonin as an antioxidant: under promises but over delivers

RJ Reiter, JC Mayo, DX Tan, RM Sainz… - Journal of pineal …, 2016 - Wiley Online Library
Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

Mitochondria: It is all about energy

A Casanova, A Wevers, S Navarro-Ledesma… - Frontiers in …, 2023 - frontiersin.org
Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Melatonin and its relationship to plant hormones

MB Arnao, J Hernández-Ruiz - Annals of Botany, 2018 - academic.oup.com
Background Plant melatonin appears to be a multi-regulatory molecule, similar to those
observed in animals, with many specific functions in plant physiology. In recent years, the …