Structural and spectroscopic studies related to vanadium chemistry and biochemistry

EJ Baran - Coordination Chemistry Reviews, 2024 - Elsevier
Different aspects of the chemistry and biochemistry of vanadium are analyzed in this review.
The preparation and characterization of oxovanadates and polyoxovanadates, including …

Interaction of vanadium complexes with proteins: revisiting the reported structures in the protein data bank (PDB) since 2015

MFA Santos, JC Pessoa - Molecules, 2023 - mdpi.com
The structural determination and characterization of molecules, namely proteins and
enzymes, is crucial to gaining a better understanding of their role in different chemical and …

Interaction of V IV O–8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization

G Ferraro, L Vitale, G Sciortino, F Pisanu… - Inorganic Chemistry …, 2023 - pubs.rsc.org
Herein, we studied the interaction of bovine pancreatic ribonuclease (RNase A) with [VIVO
(8-HQ) 2]–a promising antitrypanosomal, antituberculosis, and antitumor vanadium complex …

Implications of Protein Interaction in the Speciation of Potential VIVO–Pyridinone Drugs

G Ferraro, M Paolillo, G Sciortino, F Pisanu… - Inorganic …, 2023 - ACS Publications
Vanadium complexes (VCs) are promising agents for the treatment, among others, of
diabetes and cancer. The development of vanadium-based drugs is mainly limited by a …

A Series of Non-Oxido VIV Complexes of Dibasic ONS Donor Ligands: Solution Stability, Chemical Transformations, Protein Interactions, and Antiproliferative Activity

A Banerjee, SA Patra, G Sahu, G Sciortino… - Inorganic …, 2023 - ACS Publications
A series of mononuclear non-oxido vanadium (IV) complexes,[VIV (L1–4) 2](1–4), featuring
tridentate bi-negative ONS chelating S-alkyl/aryl-substituted dithiocarbazate ligands H2L1 …

Multiple and variable binding of pharmacologically active Bis (maltolato) oxidovanadium (IV) to lysozyme

G Ferraro, M Paolillo, G Sciortino, E Garribba… - Inorganic …, 2022 - ACS Publications
The interaction with proteins of metal-based drugs plays a crucial role in their transport,
mechanism, and activity. For an active ML n complex, where L is the organic carrier, various …

Halogenated non-innocent vanadium (V) Schiff base complexes: chemical and anti-proliferative properties

AA Haase, SA Markham, HA Murakami… - New Journal of …, 2024 - pubs.rsc.org
A series of non-innocent halogen substituted Schiff base vanadium catecholates were
added with different electron donating and withdrawing substituents on the catecholates to …

Unexpected in crystallo reactivity of the potential drug bis (maltolato) oxidovanadium (IV) with lysozyme

M Paolillo, G Ferraro, I Cipollone, E Garribba… - Inorganic Chemistry …, 2024 - pubs.rsc.org
The high-resolution X-ray structure of the adduct formed upon the reaction of hen egg white
lysozyme (HEWL) with the potential drug BMOV (bis (maltolato) oxidovanadium (IV) or [VIVO …

Facing diseases caused by trypanosomatid parasites: rational design of multifunctional oxidovanadium (IV) complexes with bioactive ligands

G Scalese, I Machado, F Salazar, EL Coitiño… - Frontiers in Chemical …, 2024 - frontiersin.org
Searching for new prospective drugs against Chagas disease (American trypanosomiasis)
and Leishmaniasis, a series of five heteroleptic vanadium compounds,[VIVO (LH)(mpo)] …

Protein‐Protein Stabilization in VIVO/8‐Hydroxyquinoline–Lysozyme Adducts

M Paolillo, G Ferraro, F Pisanu… - … A European Journal, 2024 - Wiley Online Library
The binding of the potential drug [VIVO (8‐HQ) 2], where 8‐HQ is 8‐hydroxyquinolinato, with
hen egg white lysozyme (HEWL) was evaluated through spectroscopic (electron …