Sarcoidosis is a heterogeneous disease in terms of presentation, duration, and severity. Due
to this heterogeneity, it is difficult to align treatment decisions. Biomarkers have proved to be …

Sarcoidosis is a systemic disease of unknown etiology defined by the presence of
noncaseating granulomatous inflammation that can cause organ damage and diminished …

Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis
still remain unknown. Most researchers allude to the possible autoimmune or immune …

Sarcoidosis is a systemic granulomatous disease that develops due to the Th1, Th17 and
Treg lymphocytes disturbance. There is an assumption, that B cells and follicular T-helper …

Sarcoidosis is a granulomatous multiorgan disease, thought to result from exposure to yet
unidentified antigens in genetically susceptible individuals. The exaggerated inflammatory …

Granulomas are clusters of immune cells. These structures can be formed in reaction to
infection and display signs of necrosis, such as in tuberculosis. Alternatively, in several …

Background Sarcoidosis is a multisystemic disease of unknown etiology characterized by a
disproportionate Th1 granulomatous immune response in the organs involved. Plasmatic …

Rationale: Recent observations of abnormal immunoglobulin responses and case reports
describing successful B-cell ablative therapy suggest involvement of B cells in the …

Sarcoidosis is a multi-organ granulomatous inflammatory disease of unknown etiology. Over
50% of patients will require treatment at some point in their disease and 10%–30% will …

Sarcoidosis is a systemic inflammatory disease characterized by development of
granulomas in the affected organs. Sarcoidosis is often a diagnosis of exclusion, and …