Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

Invasive fungal infections represent an expanding threat to public health. During the past
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …

Invasive fungal infections pose a serious threat to public health and are associated with high
mortality and incidence rates. The development of novel antifungal agents is urgently …

Candida auris emerges as an important causative agent of fungal infections, with worrisome
mortality rates, mainly in immunocompromised individuals. This scenario is worsened by the …

Five new difluorinated biphenyl compounds, 4′-(tert-butyl)-3, 4-difluoro-1, 1′-biphenyl
(TBDFBP), 1-(3′, 4′-difluoro-[1, 1′-biphenyl]-4-yl) ethanone (DFBPE), 3′, 4′-difluoro …

Worldwide, invasive candidiasis are a burden for the health system due to difficulties to
manage patients, to the increasing of the resistance of the current therapeutics and the …

Novel substituted monohydrazides synthesized for this study displayed broad-spectrum
activity against various fungal strains, including a panel of clinically relevant Candida auris …

This work involves the synthesis of the Co (II), Ni (II), Cu (II), Pd (II), and Pt (IV) complexes
(M1-M5) with a new Schiff base ligand by the condensation reaction of 3, 4, 5 …

A green protocol with high productivity for synthesizing hydrazone derivatives through
condensation method between aromatic hydrazines and aldehydes and ketones is …

In this study, a new synthetic method was developed for new 3-oxobutanohydrazide
derivatives. This synthetic method consists of two steps. In the first step, aldehyde phenyl …