The mechanisms of action of the dietary components of the Mediterranean diet are reviewed
in prevention of cardiovascular disease, stroke, age-associated cognitive decline and …

Vitamin B12 deficiency is a common problem in elderly subjects. If a serum cobalamin level
of about 150 pmol/L (200 pg/mL) is considered normal, 10–15% of the elderly are deficient …

The objective of this review is to provide an overview of nutritional factors involved in
cognitive aging and dementia with a focus on nutrients that are also important in …

Background: Despite widespread use of multivitamin supplements, their effect on cognitive
health—a critical issue with aging—remains inconclusive. To date, no long-term clinical …

Many epidemiologic studies have considered whether markers of B-vitamin status are
associated with cognitive function and cognitive decline. This avenue of research was …

DEMENTIA IS HIGHLY PREVALENT AMONG ELDERLY PEOPLE, and projections show
that the number of people affected might triple over the next 50 years, mainly because of a …

DNA methylation and other epigenetic factors are important in the pathogenesis of late-
onset Alzheimer's disease (LOAD). Methylenetetrahydrofolate reductase (MTHFR) gene …

Objectives: To assess the relations between homocysteine levels and neurobehavioral test
scores representing a broad range of cognitive domains in a population‐based study of …

Background: In some prospective studies, associations of serum vitamin B12 and
homocysteine concentrations with cognitive decline have been reported but few have …

Background and objective: Elevated homocysteine has been associated with a higher
prevalence of cerebral white-matter lesions and infarcts, and worse cognitive performance …