[HTML][HTML] Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence

X Xu, H Yi, J Wu, T Kuang, J Zhang, Q Li, H Du… - Biomedicine & …, 2021 - Elsevier
The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

The metabolism of berberine and its contribution to the pharmacological effects

K Wang, X Feng, L Chai, S Cao, F Qiu - Drug metabolism reviews, 2017 - Taylor & Francis
Berberine, a bioactive alkaloid isolated from several herbal substances, possesses multiple
pharmacological effects, including antimicrobial, antidiabetic, anticancer activities …

Current knowledge and pharmacological profile of berberine: an update

A Kumar, K Chopra, M Mukherjee… - European journal of …, 2015 - Elsevier
Berberine, a benzylisoquinoline alkaloid, occurs as an active constituent in numerous
medicinal plants and has an array of pharmacological properties. It has been used in …

Berberis Vulgaris and Berberine: An Update Review

M Imenshahidi, H Hosseinzadeh - Phytotherapy research, 2016 - Wiley Online Library
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

NS Yarla, A Bishayee, G Sethi, P Reddanna… - Seminars in cancer …, 2016 - Elsevier
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

Application of berberine on treating type 2 diabetes mellitus

B Pang, LH Zhao, Q Zhou, TY Zhao… - International journal …, 2015 - Wiley Online Library
Traditional Chinese medicine (TCM) performs a good clinical practice and is showing a
bright future in the treatment of diabetes mellitus (DM). TCM treatment has certain …

Current status of herbal medicines in chronic liver disease therapy: the biological effects, molecular targets and future prospects

M Hong, S Li, HY Tan, N Wang, SW Tsao… - International journal of …, 2015 - mdpi.com
Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver
disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis …

Tissue distribution of berberine and its metabolites after oral administration in rats

XS Tan, JY Ma, R Feng, C Ma, WJ Chen, YP Sun, J Fu… - PloS one, 2013 - journals.plos.org
Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as
cholesterol-lowering, anti-diabetes, cardiovascular protection and anti-inflammation …

The pharmacological activity of berberine, a review for liver protection

M Zhou, Y Deng, M Liu, L Liao, X Dai, C Guo… - European Journal of …, 2021 - Elsevier
Liver plays an important role in bile synthesis, metabolic function, degradation of toxins, new
substances synthesis in body. However, hepatopathy morbidity and mortality are increasing …

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats

HM Hussien, A Abd-Elmegied, DA Ghareeb… - Food and chemical …, 2018 - Elsevier
Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in
the precipitation of abnormal β-amyloid protein and hyper-phosphorylated tau, the main …