Human glycocalyx shedding: systematic review and critical appraisal

RG Hahn, V Patel, RO Dull - Acta Anaesthesiologica …, 2021 - Wiley Online Library
Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

A microscopic view on the renal endothelial glycocalyx

MJC Dane, BM van den Berg, DH Lee… - American Journal …, 2015 - journals.physiology.org
Endothelial cells perform key homeostatic functions such as regulating blood flow,
permeability, and aiding immune surveillance for pathogens. While endothelial activation …

Endothelial glycocalyx damage in kidney disease correlates with uraemic toxins and endothelial dysfunction

H Liew, MA Roberts, A Pope, LP McMahon - BMC nephrology, 2021 - Springer
Background Damage to the endothelial glycocalyx is an early indicator of vascular damage
and a potential marker of endothelial dysfunction. This study aimed to assess the …

Impaired endothelial glycocalyx predicts adverse outcome in subjects without overt cardiovascular disease: a 6-year follow-up study

I Ikonomidis, J Thymis, P Simitsis, GA Koliou… - Journal of …, 2021 - Springer
We investigated whether disturbance of glycocalyx integrity is related with increased
cardiovascular risk. In 600 healthy subjects, we measured perfused boundary region (PBR) …

Assessment of the sublingual microcirculation with the GlycoCheck system: Reproducibility and examination conditions

MK Eickhoff, SA Winther, TW Hansen, LJ Diaz… - PloS one, 2020 - journals.plos.org
Background The glycocalyx is an extracellular layer lining the lumen of the vascular
endothelium, protecting the endothelium from shear stress and atherosclerosis and …

Endothelial function in pulmonary arterial hypertension: from bench to bedside

M Correale, F Chirivì, EML Bevere, L Tricarico… - Journal of Clinical …, 2024 - mdpi.com
Pulmonary arterial hypertension is a complex pathology whose etiology is still not
completely well clarified. The pathogenesis of pulmonary arterial hypertension involves …

Endothelial glycocalyx in health and kidney disease: Rising star or false Dawn?

H Liew, MA Roberts, R MacGinley, LP McMahon - Nephrology, 2017 - Wiley Online Library
The endothelial glycocalyx is a layer comprised of proteins and carbohydrates on the
luminal surface of vascular endothelial cells, thought to have an important role in the health …

Layer upon layer: the functional consequences of disrupting the glycocalyx-endothelial barrier in vivo and in vitro

FRE Curry - Cardiovascular research, 2017 - academic.oup.com
The paper by Lukasz et al. 1 in this issue contributes to the growing understanding of the
role of the glycocalyx in microvascular function, not only because it describes a novel role for …

Microvascular permeability after an acute and chronic salt load in healthy subjects: a randomized open-label crossover intervention study

NMG Rorije, RHG Olde Engberink, Y Chahid… - …, 2018 - pubs.asahq.org
Background Sodium-induced microcirculatory changes, endothelial surface layer alterations
in particular, may play an important role in sodium-mediated blood pressure elevation …

Sublingual endothelial glycocalyx and atherosclerosis. A cross-sectional study

L Valerio, RJ Peters, AH Zwinderman… - PloS one, 2019 - journals.plos.org
Background Damage to endothelial glycocalyx is thought to be an early marker of
atherosclerosis and measuring reduced glycocalyx size clinically via the Perfused Boundary …