Innovations in information and communication technology infuse all branches of science,
including life sciences. Nevertheless, healthcare is historically slow in adopting …

Introduction A new body of evidence depicts the applications of artificial intelligence and
systems biology in vaccine design and development. The combination of both approaches …

The conventional approach for designing vaccine against a particular disease involves
stimulation of the immune system using the whole pathogen responsible for the disease. In …

The SARS-CoV-2 pandemic urgently calls for the development of effective preventive tools.
COVID-19 hits greatly the elder and more fragile fraction of the population boosting the …

COVID-19 pandemic has resulted in millions of deaths and a social-economic crisis. A
worldwide effort was made to develop efficient vaccines for this disease. A vaccine should …

Vaccination stands alone as an unparalleled medical intervention able to save human lives
numbering hundreds of millions. Modern licensed vaccines are either whole organism …

Although sex and gender are recognized as major determinants of health and immunity,
their role is rarely considered in clinical practice and public health. We identified six …

The lack of knowledge about the absorption, distribution, metabolism, and excretion (ADME)
of vaccines makes biopharmaceutical optimization difficult. This was shown during the …

Abstract Purpose of Review Computational and mathematical modeling have become a
critical part of understanding in-host infectious disease dynamics and predicting effective …

The lack of knowledge about the absorption, distribution, metabolism, and excretion (ADME)
of vaccines makes former biopharmaceutical optimization difficult. This was shown during …