Oxidative stress is one of the important factors in the development of alcoholic liver disease.
The production of reactive oxygen species and other free radicals is an important feature of …

Lipid metabolic diseases have substantial morbidity and mortality rates, posing a significant
threat to human health. PPARα, a member of the peroxisome proliferator-activated receptors …

BACKGROUND Alcohol-associated liver disease (ALD) is a leading cause of liver-related
morbidity and mortality, but there are no therapeutic targets and modalities to prevent ALD …

Alcohol-related liver disease (ALD) refers to a spectrum of liver manifestations ranging from
fatty liver diseases, steatohepatitis, and fibrosis/cirrhosis with chronic inflammation primarily …

Alcoholic liver disease (ALD) is a worldwide health threaten lack of effective treatment. Gut
dysbiosis and concomitant augmented intestinal permeability are strongly implicated in the …

In peroxisomes, acyl-CoA oxidase (ACOX) oxidizes fatty acids and produces H 2 O 2, and
the latter is decomposed by catalase. If ethanol is present, ethanol will be oxidized by …

Alcohol-associated liver disease (ALD) is a spectrum of diseases, the onset and progression
of which are due to chronic alcohol use. ALD ranges, by increasing severity, from hepatic …

Liver fat storage, also called hepatic steatosis, is increasingly common and represents a
very frequent diagnosis in the medical field. Excess fat is not without consequences. In fact …

Following its introduction as an alternative to perfluorooctanoic acid, hexafluoropropylene
oxide dimer acid (HFPO-DA) has been extensively detected in various environmental …

Liver fibrosis is the result of sustained chronic liver injury and inflammation leading to
hepatocyte cell death followed by the formation of fibrous scars, which is the hallmark of …