Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

G Raivich, M Bohatschek, CUA Kloss, A Werner… - Brain research …, 1999 - Elsevier
Damage to the central nervous system (CNS) leads to cellular changes not only in the
affected neurons but also in adjacent glial cells and endothelia, and frequently, to a …

Combinatorial therapies after spinal cord injury: how can biomaterials help?

T Führmann, PN Anandakumaran… - Advanced healthcare …, 2017 - Wiley Online Library
Traumatic spinal cord injury (SCI) results in an immediate loss of motor and sensory function
below the injury site and is associated with a poor prognosis. The inhibitory environment that …

[HTML][HTML] Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells

SH Yuan, J Martin, J Elia, J Flippin, RI Paramban… - PloS one, 2011 - journals.plos.org
Background Neural induction of human pluripotent stem cells often yields heterogeneous
cell populations that can hamper quantitative and comparative analyses. There is a need for …

Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

Y Ogawa, K Sawamoto, T Miyata… - Journal of …, 2002 - Wiley Online Library
Neural progenitor cells, including neural stem cells, are a potential expandable source of
graft material for transplantation aimed at repairing the damaged CNS. Here we present the …

Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic …

AL Vescovi, EA Parati, A Gritti, P Poulin, M Ferrario… - Experimental …, 1999 - Elsevier
Stem cells that can give rise to neurons, astroglia, and oligodendroglia have been found in
the developing and adult central nervous system (CNS) of rodents. Yet, their existence …

Stem cell therapies for spinal cord injury

V Sahni, JA Kessler - Nature Reviews Neurology, 2010 - nature.com
Stem cell therapy is a potential treatment for spinal cord injury (SCI), and a variety of different
stem cell types have been evaluated in animal models and humans with SCI. No consensus …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

Cellular transplantation strategies for spinal cord injury and translational neurobiology

PJ Reier - NeuroRx, 2004 - Elsevier
Basic science advances in spinal cord injury and regeneration research have led to a variety
of novel experimental therapeutics designed to promote functionally effective axonal …

Chondroitinase ABC enhances axonal regrowth through Schwann cell‐seeded guidance channels after spinal cord injury

CH Chau, DKY Shum, H Li, J Pei, YY Lui… - The FASEB …, 2004 - Wiley Online Library
Grafting of Schwann cell‐seeded channels into hemisected adult rat thoracic spinal cords
has been tested as a strategy to bridge the injured cord. Despite success in guiding axonal …

Establishment and Properties of Neural Stem Cell Clones: Plasticity In Vitro and In Vivo

AL Vescovi, EY Snyder - Brain pathology, 1999 - Wiley Online Library
The study of the basic physiology of the neural precursors generated during brain
development is driven by two inextricably linked goals. First, such knowledge is instrumental …