Biomedical research requires both in vitro and in vivo studies in order to explore disease
processes or drug interactions. Foundational investigations have been performed at the …

The interplay between genetic transformations, biochemical communications, and physical
interactions is crucial in cancer progression. Metastasis, a leading cause of cancer-related …

Endochondral ossification (EO) is an essential biological process than underpins how
human bones develop, grow, and heal in the event of a fracture. So much is unknown about …

Cancer cell extravasation, a key step in the metastatic cascade, involves cancer cell arrest
on the endothelium, transendothelial migration (TEM), followed by the invasion into the …

The remarkable contractility and force generation ability exhibited by cancer cells empower
them to overcome the resistance and steric hindrance presented by a three-dimensional …

Ever since the implementation of microfluidics in the biomedical field, in vitro models have
experienced unprecedented progress that has led to a new generation of highly complex …

Congenital athymia is a life-limiting disorder due to rare inborn errors of immunity causing
impaired thymus organogenesis or abnormal thymic stromal cell development and function …

The thymus is the key immune organ for the development of T cells. Different populations of
thymic stromal cells interact with T cells, thereby controlling the dynamic development of T …

Vascularization is driven by morphogen signals and mechanical cues that coordinately
regulate cellular force generation, migration, and shape change to sculpt the developing …