A biosocial return to race? A cautionary view for the postgenomic era
Recent studies demonstrating epigenetic and developmental sensitivity to early
environments, as exemplified by fields like the Developmental Origins of Health and …
environments, as exemplified by fields like the Developmental Origins of Health and …
Map of epigenetic age acceleration: a worldwide analysis
I Yusipov, A Kalyakulina, A Trukhanov… - Ageing Research …, 2024 - Elsevier
We present a systematic analysis of epigenetic age acceleration based on by far the largest
collection of publicly available DNA methylation data for healthy samples (93 datasets, 23 K …
collection of publicly available DNA methylation data for healthy samples (93 datasets, 23 K …
Novel diagnostic DNA methylation episignatures expand and refine the epigenetic landscapes of Mendelian disorders
MA Levy, H McConkey, J Kerkhof… - Human Genetics and …, 2022 - cell.com
Overlapping clinical phenotypes and an expanding breadth and complexity of genomic
associations are a growing challenge in the diagnosis and clinical management of …
associations are a growing challenge in the diagnosis and clinical management of …
Body mass index, adverse pregnancy outcomes, and cardiovascular disease risk
BACKGROUND: Obesity is a well-established risk factor for both adverse pregnancy
outcomes (APOs) and cardiovascular disease (CVD). However, it is not known whether …
outcomes (APOs) and cardiovascular disease (CVD). However, it is not known whether …
Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data
Background Genomic technologies can be subject to significant batch-effects which are
known to reduce experimental power and to potentially create false positive results. The …
known to reduce experimental power and to potentially create false positive results. The …
An integrative framework and recommendations for the study of DNA methylation in the context of race and ethnicity
Human social epigenomics research is critical to elucidate the intersection of social and
genetic influences underlying racial and ethnic differences in health and development …
genetic influences underlying racial and ethnic differences in health and development …
Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings
M Dapas, EE Thompson, W Wentworth-Sheilds… - PLoS …, 2023 - journals.plos.org
Impaired lung function in early life is associated with the subsequent development of chronic
respiratory disease. Most genetic associations with lung function have been identified in …
respiratory disease. Most genetic associations with lung function have been identified in …
Differential DNA methylation by Hispanic ethnicity among firefighters in the United States
JM Goodrich, MA Furlong… - Epigenetics …, 2021 - journals.sagepub.com
Firefighters are exposed to a variety of environmental hazards and are at increased risk for
multiple cancers. There is evidence that risks differ by ethnicity, yet the biological or …
multiple cancers. There is evidence that risks differ by ethnicity, yet the biological or …
A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data
Background: Recent studies have identified thousands of associations between DNA
methylation CpGs and complex diseases/traits, emphasizing the critical role of epigenetics …
methylation CpGs and complex diseases/traits, emphasizing the critical role of epigenetics …
[PDF][PDF] Dynamics of methylation of CpG sites associated with systemic lupus erythematosus subtypes in a longitudinal cohort
CM Lanata, J Nititham, KE Taylor… - Arthritis & …, 2022 - Wiley Online Library
Objective Findings from cross‐sectional studies have revealed associations between DNA
methylation and systemic lupus erythematosus (SLE) outcomes. This study was undertaken …
methylation and systemic lupus erythematosus (SLE) outcomes. This study was undertaken …