[HTML][HTML] Dopaminergic neurons and brain reward pathways: from neurogenesis to circuit assembly

SX Luo, EJ Huang - The American journal of pathology, 2016 - Elsevier
Midbrain dopaminergic (DA) neurons in the substantia nigra pars compacta and ventral
tegmental area regulate extrapyramidal movement and important cognitive functions …

N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development

Y Miyamoto, F Sakane, K Hashimoto - Cell adhesion & migration, 2015 - Taylor & Francis
This review addresses our current understanding of the regulatory mechanism by which N-
cadherin, a classical cadherin, affects neural progenitor cells (NPCs) during development. N …

Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS

H Lee, JJ Lee, NY Park, SK Dubey, T Kim, K Ruan… - Nature …, 2021 - nature.com
Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons
degenerate, the causes of which remain unclear. In particular, the basis for selective …

Wnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis

M Joksimovic, R Awatramani - Journal of molecular cell biology, 2014 - academic.oup.com
Loss of midbrain dopaminergic (mDA) neurons underlies the motor symptoms of Parkinson's
disease. Towards cell replacement, studies have focused on mechanisms underlying …

Genetic control of midbrain dopaminergic neuron development

S Blaess, SL Ang - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
Midbrain dopaminergic neurons are involved in regulating motor control, reward behavior,
and cognition. Degeneration or dysfunction of midbrain dopaminergic neurons is implicated …

Differential neuronal plasticity of dental pulp stem cells from exfoliated deciduous and permanent teeth towards dopaminergic neurons

D Majumdar, M Kanafi, R Bhonde… - Journal of cellular …, 2016 - Wiley Online Library
Based on early occurrence in chronological age, stem‐cells from human exfoliated
deciduous teeth (SHED) has been reported to possess better differentiation‐potential toward …

[HTML][HTML] Establishing diversity in the dopaminergic system

GO Bodea, S Blaess - FEBS letters, 2015 - Elsevier
Midbrain dopaminergic neurons (MbDNs) modulate cognitive processes, regulate voluntary
movement, and encode reward prediction errors and aversive stimuli. While the …

[HTML][HTML] Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain

M Gazea, E Tasouri, M Tolve, V Bosch… - Developmental …, 2016 - Elsevier
Midbrain dopaminergic (mDA) neurons modulate various motor and cognitive functions, and
their dysfunction or degeneration has been implicated in several psychiatric diseases. Both …

Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure

ER Brooks, MT Islam, KV Anderson, JA Zallen - Elife, 2020 - elifesciences.org
Neural tube closure defects are a major cause of infant mortality, with exencephaly
accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube …

Role of Sonic Hedgehog Signaling Activation in the Prevention of Neurological Abnormalities Associated with Obsessive–Compulsive Disorder

R Gupta, S Mehan, S Chhabra, A Giri… - Neurotoxicity Research, 2022 - Springer
The smoothened sonic hedgehog (Smo-Shh) pathway is one mechanism that influences
neurogenesis, including brain cell differentiation and development during childhood. Shh …