Polymers for Disrupting Protein–Protein Interactions: Where Are We and Where Should We Be?
Protein–protein interactions (PPIs) are central to the cellular signaling and regulatory
networks that underlie many physiological and pathophysiological processes. It is …
networks that underlie many physiological and pathophysiological processes. It is …
Exploring the potential of P-glycoprotein inhibitors in the targeted delivery of anti-cancer drugs: A comprehensive review
Due to the high prevalence of cancer, progress in the management of cancer is the need of
the hour. Most cancer patients develop chemotherapeutic drug resistance, and many remain …
the hour. Most cancer patients develop chemotherapeutic drug resistance, and many remain …
Exploring the effects of pemetrexed on drug resistance mechanisms in human lung adenocarcinoma and its association with PGRMC1
SY Wu, EC Liao, YF Wen, YS Wang, H Meng… - Chemico-Biological …, 2024 - Elsevier
According to the 2022 cancer statistics of the World Health Organization, lung cancer ranks
among the top ten causes of death, with lung adenocarcinoma being the most prevalent …
among the top ten causes of death, with lung adenocarcinoma being the most prevalent …
Pharmaceutical prospects of pomegranate antioxidants in combating microbial infections
Pomegranates, which are renowned for their diverse bioactive phytochemicals with
antioxidant, anti-inflammatory, and antimicrobial properties, have garnered significant …
antioxidant, anti-inflammatory, and antimicrobial properties, have garnered significant …
Interactions between multifunctional pharmaceutical excipients and efflux pump for optimal drug transport and bioavailability: An overview
VL Gaikwad, S Sen, PR Dhake - Journal of Drug Delivery Science and …, 2024 - Elsevier
Polymeric excipients ensure the site-specific delivery of the drug at the desired rate for a
specified duration to achieve better efficacy. Pharmaceutical excipients were supposed to be …
specified duration to achieve better efficacy. Pharmaceutical excipients were supposed to be …
[HTML][HTML] Comparing antioxidant and cytoprotective effects: Quercetin glycoside vs. aglycone from Ephedra alata
Background A wide range of chronic diseases is associated with ROS-mediated oxidative
stress. Quercetin glycoside (QG) is reported to be a powerful antioxidant with extremely high …
stress. Quercetin glycoside (QG) is reported to be a powerful antioxidant with extremely high …
Design, Synthesis, Computational Study, and Biological Evaluation of Sulfonyl Tethered Piperazine Derivatives as Antimicrobial Agents
V Thopate, SA Dhawale, R Kawale, D Gaikwad… - …, 2024 - Wiley Online Library
Piperazine, a nitrogen‐containing heterocyclic compound, has potential in medical
chemistry due to its versatile structure and ease of modification. Therefore, researchers have …
chemistry due to its versatile structure and ease of modification. Therefore, researchers have …
Investigating natural inhibitors of Permeability-glycoprotein (P-gp) liver transporter via molecular docking simulation for Hepatocellular carcinoma therapy
Abstract Permeability-glycoprotein (P-gp), a dynamic efflux pump responsible for
transporting xenobiotics and drugs out of cells, is a contributor to multidrug resistance …
transporting xenobiotics and drugs out of cells, is a contributor to multidrug resistance …
[PDF][PDF] Phytomedicine Plus
E El Maaiden, N Ullah, A Ezzariai, A Mazar, H Boukcim… - researchgate.net
Background: A wide range of chronic diseases is associated with ROS-mediated oxidative
stress. Quercetin glycoside (QG) is reported to be a powerful antioxidant with extremely high …
stress. Quercetin glycoside (QG) is reported to be a powerful antioxidant with extremely high …