neoepiscope improves neoepitope prediction with multivariant phasing

MA Wood, A Nguyen, AJ Struck, K Ellrott… - …, 2020 - academic.oup.com
Motivation The vast majority of tools for neoepitope prediction from DNA sequencing of
complementary tumor and normal patient samples do not consider germline context or the …

Misannotated multi-nucleotide variants in public cancer genomics datasets lead to inaccurate mutation calls with significant implications

S Srinivasan, N Kalinava, R Aldana, Z Li, S van Hagen… - Cancer Research, 2021 - AACR
Although next-generation sequencing is widely used in cancer to profile tumors and detect
variants, most somatic variant callers used in these pipelines identify variants at the lowest …

Mis-annotated multi nucleotide variants in public cancer genomics datasets can lead to inaccurate mutation calls with significant implications

S Srinivasan, N Kalinava, R Aldana, Z Li, S van Hagen… - bioRxiv, 2020 - biorxiv.org
Background Next generation sequencing is widely used in cancer to profile tumors and
detect variants. Most somatic variant callers used in these pipelines identify variants at the …