Current status and evolving approaches to African swine fever vaccine development
African swine fever (ASF) is a highly lethal haemorrhagic disease of swine caused by
African swine fever virus (ASFV), a unique and genetically complex virus. The disease …
African swine fever virus (ASFV), a unique and genetically complex virus. The disease …
[HTML][HTML] Rift Valley fever virus: A review of diagnosis and vaccination, and implications for emergence in Europe
Rift Valley fever virus (RVFV) is a mosquito-borne virus, and is the causative agent of Rift
Valley fever (RVF), a zoonotic disease characterised by an increased incidence of abortion …
Valley fever (RVF), a zoonotic disease characterised by an increased incidence of abortion …
Middle East respiratory syndrome coronavirus nsp1 inhibits host gene expression by selectively targeting mRNAs transcribed in the nucleus while sparing mRNAs of …
KG Lokugamage, K Narayanan, K Nakagawa… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT The newly emerged Middle East respiratory syndrome coronavirus (MERS-
CoV) and severe acute respiratory syndrome CoV (SARS-CoV) represent highly pathogenic …
CoV) and severe acute respiratory syndrome CoV (SARS-CoV) represent highly pathogenic …
An overview of Rift Valley fever vaccine development strategies
PK Kitandwe, PF McKay, P Kaleebu, RJ Shattock - Vaccines, 2022 - mdpi.com
Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that causes high fetal and
neonatal mortality in ruminants and a mild to fatal hemorrhagic fever in humans. There are …
neonatal mortality in ruminants and a mild to fatal hemorrhagic fever in humans. There are …
The envelope proteins of the Bunyavirales
P Guardado-Calvo, FA Rey - Advances in virus research, 2017 - Elsevier
Abstract The Bunyavirales Order encompasses nine families of enveloped viruses
containing a single-stranded negative-sense RNA genome divided into three segments. The …
containing a single-stranded negative-sense RNA genome divided into three segments. The …
A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion
P Guardado-Calvo, K Atkovska, SA Jeffers, N Grau… - Science, 2017 - science.org
The Rift Valley fever virus (RVFV) is transmitted by infected mosquitoes, causing severe
disease in humans and livestock across Africa. We determined the x-ray structure of the …
disease in humans and livestock across Africa. We determined the x-ray structure of the …
Advances and perspectives in the development of vaccines against highly pathogenic bunyaviruses
T Chen, Z Ding, J Lan, G Wong - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Increased human activities around the globe and the rapid development of once rural
regions have increased the probability of contact between humans and wild animals. A …
regions have increased the probability of contact between humans and wild animals. A …
A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus
M Merchant, CP Mata, Y Liu, H Zhai, AV Protasio… - Science …, 2022 - science.org
Endogenous viral elements (EVEs), accounting for 15% of our genome, serve as a genetic
reservoir from which new genes can emerge. Nematode EVEs are particularly diverse and …
reservoir from which new genes can emerge. Nematode EVEs are particularly diverse and …
Chitosan and chitosan nanoparticles as adjuvant in local Rift Valley Fever inactivated vaccine
AF El-Sissi, FH Mohamed, NM Danial, AQ Gaballah… - 3 Biotech, 2020 - Springer
The present study aimed to improve the potency of inactivated Rift Valley Fever Virus
(RVFV) vaccine using chitosan (CS) or chitosan nanoparticles (CNP) as adjuvants. Chitosan …
(RVFV) vaccine using chitosan (CS) or chitosan nanoparticles (CNP) as adjuvants. Chitosan …
Recent advances in Bunyavirus reverse genetics research: systems development, applications, and future perspectives
F Ren, S Shen, Q Wang, G Wei, C Huang… - Frontiers in …, 2021 - frontiersin.org
Bunyaviruses are members of the Bunyavirales order, which is the largest group of RNA
viruses, comprising 12 families, including a large group of emerging and re-emerging …
viruses, comprising 12 families, including a large group of emerging and re-emerging …