Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Acoustofluidics, the integration of acoustics and microfluidics, is a rapidly growing research
field that is addressing challenges in biology, medicine, chemistry, engineering, and …

Circulating tumor cells (CTCs) detach from primary or metastatic lesions and circulate in the
peripheral blood, which is considered to be the cause of distant metastases. CTC analysis in …

There is an unmet clinical need to extract living circulating tumor cells (CTCs) for functional
studies and in vitro expansion to enable drug testing and predict responses to therapy in …

Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Generating functional and perfusable micro-vascular networks is an important goal for the
fabrication of large and three-dimensional tissues. Up to now, the fabrication of micro …

Handling of submicron-sized objects is important in many biochemical and biomedical
applications, but few methods today can precisely manipulate this range of particles. We …

Efficient and reliable manipulation of biological particles is crucial in medical diagnosis and
chemical synthesis. Inertial microfluidic devices utilizing passive hydrodynamic forces in the …

Conventional bioparticle extraction requires labor-intensive operation, and expensive and
bulky centrifuges. Herein, we report a miniaturized centrifuge by cascading four paralleled …