Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Background: The majority of the human genome comprises noncoding sequences, which
are in part transcribed as long noncoding RNAs (lncRNAs). lncRNAs exhibit multiple …

Cardiovascular disease is an enormous socioeconomic burden worldwide and remains a
leading cause of mortality and disability despite significant efforts to improve treatments and …

Vast parts of mammalian genomes encode for transcripts that are not further translated into
proteins. The purpose of the majority of such noncoding ribonucleic acids (RNAs) remained …

Macrophage activation, ie, classical M1 and the alternative M2, plays a critical role in many
pathophysiological processes, such as inflammation and tissue injury and repair. Although …

Aims Inflammation is a key driver of atherosclerosis and myocardial infarction (MI), and
beyond proteins and microRNAs (miRs), long noncoding RNAs (lncRNAs) have been …

Aims The immune system is considered a key driver of atherosclerosis, and beyond proteins
and microRNAs (miRs), long non-coding RNAs (lncRNAs) are implicated in immune control …

Nucleic acid-based therapeutics are currently developed at large scale for prevention and
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …