Reductive stress‐induced mitochondrial dysfunction and cardiomyopathy

WX Ma, CY Li, R Tao, XP Wang… - Oxidative medicine and …, 2020 - Wiley Online Library
The goal of this review was to summarize reported studies focusing on cellular reductive
stress‐induced mitochondrial dysfunction, cardiomyopathy, dithiothreitol‐(DTT‐) induced …

[HTML][HTML] Distinct roles of Nrf1 and Nrf2 in monitoring the reductive stress response to dithiothreitol (DTT)

R Wufuer, Z Fan, J Yuan, Z Zheng, S Hu, G Sun… - Antioxidants, 2022 - mdpi.com
Transcription factor Nrf2 (nuclear factor, erythroid 2-like 2, encoded by Nfe2l2) has been
accepted as a key player in redox regulatory responses to oxidative or reductive stresses …

[HTML][HTML] Thiol-reducing agents abate cholestasis-induced lung inflammation, oxidative stress, and histopathological alterations

H Niknahad, A Nadgaran, S Alidaee… - Trends in …, 2023 - journals.sums.ac.ir
Cholestasis is not only influences the hepatic function but also damages many other organs.
Lung injury is a critical secondary organ damage associated with cholestasis/cirrhosis …

[HTML][HTML] Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated …

R Heidari, V Ghanbarinejad, H Mohammadi… - Biomedicine & …, 2018 - Elsevier
Cholestasis is a disorder characterized by impaired bile flow and accumulation of cytotoxic
bile acids in the liver. On the other hand, oxidative stress and its deleterious consequences …

[HTML][HTML] Oral administration of thiol-reducing agents mitigates gut barrier disintegrity and bacterial lipopolysaccharide translocation in a rat model of biliary obstruction

MM Ommati, O Farshad, H Niknahad, K Mousavi… - Current Research in …, 2020 - Elsevier
It has been well documented that cirrhosis is associated with the intestinal injury. Intestinal
injury in cirrhosis could lead to bacterial lipopolysaccharide (LPS) translocation to the …

1, 4-Dithiothreitol treatment ameliorates hematopoietic and intestinal injury in irradiated mice: Potential application of a treatment for acute radiation syndrome

K Li, J Zhang, J Cao, X Li, H Tian - International immunopharmacology, 2019 - Elsevier
Radiation exposure poses a significant threat to public health, which can lead to acute
hematopoietic system and intestinal system injuries due to their higher radiation sensitivity …

Antibiotic residues in honey: a public health issue

CMG Lima, FM Dalla Nora, SKT Seraglio… - Research, Society and …, 2020 - rsdjournal.org
Honey has numerous uses and composes formulations of many food, pharmaceutical, and
cosmetic products due to its chemical, biological, and sensorial characteristics. In recent …

[HTML][HTML] Reversible thiol oxidation increases mitochondrial electron transport complex enzyme activity but not respiration in cardiomyocytes from patients with end …

RA Kumar, T Thome, OM Sharaf, TE Ryan… - Cells, 2022 - mdpi.com
Cardiomyocyte dysfunction in patients with end-stage heart failure with reduced ejection
fraction (HFrEF) stems from mitochondrial dysfunction, which contributes to an energetic …

[PDF][PDF] Alpha Lipoic acid role on pituitary testicular function in mice treated with Nitrofurantoin or Methotrexate

T Al-Azawi, MH Asker - J. Entomol. Zool. Stud, 2017 - entomoljournal.com
This experiment was designed to investigate the antioxidative role of alpha lipoic acid
against the reproductive adverse effect of some drugs. Thirty adult male swiss albino mice …

Dietary Risks Assessment of Antibiotic Residues and Microbial Safety of Local Honey in Adamawa State

FB Dowell, ON Maitera, MW Daniel… - American Journal of …, 2022 - journals.e-palli.com
This study investigated the microbial safety and dietary risk assessments of antibiotic
residues in honey. The determination of antibiotic residues in this study were carried out …