Infections caused by non-tuberculous mycobacteria (NTM) are increasing globally and are
notoriously difficult to treat due to intrinsic resistance of these bacteria to many common …

The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …

Virulence is described as an ability of an organism to infect the host and cause a disease.
Virulence factors are the molecules that assist the bacterium colonize the host at the cellular …

The aryl hydrocarbon receptor (AhR) is a highly conserved ligand-dependent transcription
factor that senses environmental toxins and endogenous ligands, thereby inducing …

Tuberculosis (TB), caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb),
remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette …

Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

Efforts over the last 2 decades have led to a rich research and development pipeline of
tuberculosis (TB) vaccines. Although none of the candidates has successfully completed the …

Mycobacterium tuberculosis (Mtb) is one of the most life-threatening mycobacterial species
which is increasing the death rate due to emerging multi-drug resistant (MDR) strains …

The current state-of-the-art tests for infection with Mycobacterium tuberculosis–the IFN-γ
release assays–rely on accurate measurement of the cytokine IFN-γ. Many other potential …