Context-specific stress causes compartmentalized SARM1 activation and local degeneration in cortical neurons

FI Hinz, CLM Villegas, JT Roberts, H Yao… - Journal of …, 2024 - Soc Neuroscience
Sterile alpha and TIR motif containing 1 (SARM1) is an inducible NADase that localizes to
mitochondria throughout neurons and senses metabolic changes that occur after injury …

[HTML][HTML] Novel high-content and open-source image analysis tools for profiling mitochondrial morphology in neurological cell models

MY Chin, DA Joy, M Samaddar, A Rana, J Chow… - SLAS Discovery, 2025 - Elsevier
Mitochondria undergo dynamic morphological changes depending on cellular cues, stress,
genetic factors, or disease. The structural complexity and disease-relevance of mitochondria …