[HTML][HTML] Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies

JS Bhatti, GK Bhatti, PH Reddy - … et Biophysica Acta (BBA)-Molecular Basis …, 2017 - Elsevier
Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …

Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

N Sallam, I Laher - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

Lactate transport and signaling in the brain: potential therapeutic targets and roles in body—Brain interaction

LH Bergersen - Journal of Cerebral Blood Flow & …, 2015 - journals.sagepub.com
Lactate acts as a 'buffer'between glycolysis and oxidative metabolism. In addition to being
exchanged as a fuel by the monocarboxylate transporters (MCTs) between cells and tissues …

Macrophage polarization mediated by mitochondrial dysfunction induces adipose tissue inflammation in obesity

L Xu, X Yan, Y Zhao, J Wang, B Liu, S Yu, J Fu… - International journal of …, 2022 - mdpi.com
Obesity is one of the prominent global health issues, contributing to the growing prevalence
of insulin resistance and type 2 diabetes. Chronic inflammation in adipose tissue is …

Mechanisms of myofascial pain

MS Jafri - International scholarly research notices, 2014 - Wiley Online Library
Myofascial pain syndrome is an important health problem. It affects a majority of the general
population, impairs mobility, causes pain, and reduces the overall sense of well‐being …

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

G Giuliani, M Rosina, A Reggio - The FEBS journal, 2022 - Wiley Online Library
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has
contributed to modify the monocentric view of muscle regeneration beyond muscle satellite …

Lifestyle modifications and nutritional interventions in aging-associated cognitive decline and Alzheimer's disease

GK Bhatti, AP Reddy, PH Reddy… - Frontiers in aging …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a type of incurable neurodegenerative disease that is
characterized by the accumulation of amyloid-β (Aβ; plaques) and tau hyperphosphorylation …

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

F Pala, D Di Girolamo, S Mella, S Yennek… - Journal of cell …, 2018 - journals.biologists.com
During growth, homeostasis and regeneration, stem cells are exposed to different energy
demands. Here, we characterise the metabolic pathways that mediate the commitment and …

OPA 1 deficiency promotes secretion of FGF 21 from muscle that prevents obesity and insulin resistance

RO Pereira, SM Tadinada, FM Zasadny… - The EMBO …, 2017 - embopress.org
Mitochondrial dynamics is a conserved process by which mitochondria undergo repeated
cycles of fusion and fission, leading to exchange of mitochondrial genetic content, ions …