Early breast cancer detection using untargeted and targeted metabolomics

Y Wei, P Jasbi, X Shi, C Turner, J Hrovat… - Journal of proteome …, 2021 - ACS Publications
Breast cancer (BC) is a common cause of morbidity and mortality, particularly in women.
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …

Stereoisomers in sports drug testing: analytical strategies and applications

A Thomas, M Thevis - Journal of Chromatography A, 2022 - Elsevier
Analytics employed in modern doping controls are designed to cover an extensive range of
rather diverse classes of substances, all of which are banned in sport according to the list of …

Zebrafish (Danio rerio) water tank model for the investigation of drug metabolism: Progress, outlook, and challenges

VF Sardela, CS Anselmo, IKC Nunes… - Drug Testing and …, 2018 - Wiley Online Library
Zebrafish (Danio rerio) water tank (ZWT) approach was investigated as an alternative model
for metabolism studies based on six different experiments with four model compounds …

DART-MS/MS screening for the determination of 1, 3-dimethylamylamine and undeclared stimulants in seized dietary supplements from Brazil

MK dos Santos, E Gleco, JT Davidson, GP Jackson… - Forensic Chemistry, 2018 - Elsevier
dimethylamylamine (DMAA) is an alkylamine with stimulating properties that has been used
predominantly as an additive in dietary supplements. DMAA is mostly consumed by …

Multiresidue pesticide analysis in nutraceuticals from green tea extracts by comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry

W Jia, X Chu, F Zhang - Journal of Chromatography A, 2015 - Elsevier
A new analytical method was developed and validated for simultaneous analysis of 423
pesticides, isomers, and pesticide metabolites in nutraceutical products obtained from green …

[HTML][HTML] Application of a bar adsorptive microextraction based methodology for doping control of alkylamine stimulants in urine matrices

CVP Almeida, NR Neng, JMF Nogueira… - Journal of Chromatography …, 2024 - Elsevier
Abstract To comply with 'World Anti-Doping Agency'(WADA) guidelines, doping control
laboratories must continuously adjust their analytical procedures. Therefore, sample …

Stimulant doping agents used in Brazil: prevalence, detectability, analytical implications, and challenges

HMG Pereira, VF Sardela - Substance use & misuse, 2014 - Taylor & Francis
This article presents the prevalence of stimulant doping among Brazilian athletes, the
analytical approaches used, as well as a general evolution of the detectability of the …

Application of nucleophilic substitution reaction for sensitive determination of heptaminol hydrochloride in pharmaceuticals

M Abdelgaleel, DM Nagi, M Oraby, SM Derayea… - BMC chemistry, 2024 - Springer
A straightforward and sensitive spectrofluorimetric approach was established for the
determination of heptaminol hydrochloride (HTM-HCl) based on the derivatization of the …

[HTML][HTML] Fast ephedrine quantification by gas chromatography mass spectrometry

GRA Carneiro, A Silva, RM Cavalcante… - Journal of the Brazilian …, 2018 - SciELO Brasil
Ephedrines are widely used in therapy. Because of their stimulant properties, these
substances are relevant in different forensic fields. At present, the state of the art for …

Development of analytical method for determination of 1, 3‐dimethylamylamine in sports nutrition and bodybuilding supplements using pH‐switchable deep eutectic …

D Shen, J Zhang, Y Zhang, X Du - Journal of Separation …, 2024 - Wiley Online Library
In this work, an easy, safe, simple, and efficient pH‐switchable deep eutectic solvents
(DESs)‐based liquid phase microextraction followed by high‐performance liquid …